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CD3 antibody

Name: CD3 antibody
SKU: ABIN1177370
Availability: OutOfStock

CD3 Reactivity: Human FACS, Func Host: Mouse Monoclonal HIT3a unconjugated

FACS

1 image

Catalog No. ABIN1177370

Datasheet as PDF

Target See all CD3 Antibodies

CD3
Reactivity
181

90

23

15

15

10

8

8

7

5

3

3

2

1
Human
Host
207

45

14

13

9
Mouse
Compatible Secondaries
Clonality
277

7
Monoclonal
Conjugate
85

33

27

22

21

11

7

6

6

5

4

3

3

3

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CD3 antibody is un-conjugated
Application
260

80

54

44

43

35

28

23

9

8

8

7

4

3

2

2

2

2

2

2

2

1
Flow Cytometry (FACS), Functional Studies (Func)

Brand

BD Pharmingen™

Purification

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Sterility

0.2 μm filtered

Endotoxin Level

Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.

Clone

HIT3a

Isotype

IgG2a kappa

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anti-CD3 (CD3) antibody
CD3 Reactivity: Human FACS, IP, Func, CyTOF Host: Mouse Monoclonal MEM-57 unconjugated

anti-CD3 (CD3) antibody
CD3 Reactivity: Human, Non-Human Primate FACS, IP, IHC (fro), Func, CyTOF Host: Mouse Monoclonal UCHT1 unconjugated

anti-CD3 (CD3) antibody (Biotin)
CD3 Reactivity: Human FACS, IP Host: Mouse Monoclonal MEM-57 Biotin

anti-CD3 (CD3) antibody (Biotin)
CD3 Reactivity: Human, Non-Human Primate FACS, IP, IHC (fro) Host: Mouse Monoclonal UCHT1 Biotin

anti-CD3 (CD3) antibody (APC)
CD3 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal UCHT1 APC

anti-CD3 (CD3) antibody (PerCP)
CD3 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal UCHT1 PerCP

anti-CD3 (CD3) antibody (PE)
CD3 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal UCHT1 PE

Restrictions

For Research Use only
Format

Liquid

Concentration

1.0 mg/mL

Buffer

No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.

Preservative

Azide free

Storage

4 °C

Storage Comment

Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Target

CD3

Alternative Name

CD3 (CD3 Products)

Synonyms

CD3 antibody, AI504783 antibody, CD3epsilon antibody, T3e antibody, cd3-gamma antibody, cd3g antibody, cd3g-a antibody, cd3g/d antibody, cd3gd antibody, t3g antibody, CD3e molecule antibody, CD3d molecule antibody, CD3 antigen, epsilon polypeptide antibody, CD3g molecule S homeolog antibody, CD3E antibody, CD3D antibody, Cd3e antibody, cd3g.S antibody

Background

Reacts with the human epsilon-chain, a 20 kDa subunit of CD3/T cell antigen receptor complex found on 70-80% of normal human peripheral blood lymphocytes and 60-85% of thymocytes. Studies from the HLDA Workshop show this antibody to be mitogenic when used in conjuction with pokeweed mitogen. CD3 plays a role in signal transduction during antigen recognition. HIT3a antibody does not stain intracellular CD3 unlike the other CD3 clone, UCHT1.

Pathways

TCR Signaling, Ubiquitin Proteasome Pathway