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CD3 antibody

Name: CD3 antibody
SKU: ABIN1177371
Availability: OutOfStock

CD3 Reactivity: Rhesus Monkey, Cynomolgus, Baboon FACS Host: Mouse Monoclonal SP34 unconjugated

(1 reference)

Catalog No. ABIN1177371

Datasheet as PDF

Target See all CD3 Antibodies

CD3
Reactivity
181

90

22

15

15

10

8

8

7

5

3

3

2

1
Rhesus Monkey, Cynomolgus, Baboon
Host
206

45

14

13

9
Mouse
Compatible Secondaries
Clonality
276

7
Monoclonal
Conjugate
85

32

27

22

21

11

7

6

6

5

4

3

3

3

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CD3 antibody is un-conjugated
Application
259

79

53

44

42

35

28

23

9

8

7

7

4

3

2

2

2

2

2

2

2

1
Flow Cytometry (FACS)

Brand

BD Pharmingen™

Purification

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Sterility

0.2 μm filtered

Endotoxin Level

Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.

Clone

SP34

Isotype

IgG3 lambda

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anti-CD3 (CD3) antibody
CD3 Reactivity: Human, Non-Human Primate FACS, IP, IHC (fro), Func, CyTOF Host: Mouse Monoclonal UCHT1 unconjugated

anti-CD3 (CD3) antibody (Biotin)
CD3 Reactivity: Human FACS, IP Host: Mouse Monoclonal MEM-57 Biotin

anti-CD3 (CD3) antibody (Biotin)
CD3 Reactivity: Human, Non-Human Primate FACS, IP, IHC (fro) Host: Mouse Monoclonal UCHT1 Biotin

anti-CD3 (CD3) antibody (APC)
CD3 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal UCHT1 APC

anti-CD3 (CD3) antibody (PerCP)
CD3 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal UCHT1 PerCP

anti-CD3 (CD3) antibody (PE)
CD3 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal UCHT1 PE

Restrictions

For Research Use only
Format

Liquid

Concentration

1.0 mg/mL

Buffer

No azide/low endotoxin: Aqueous buffered solution containing protein stabilizer, no preservative, 0.2μm sterile filtered.

Preservative

Azide free

Storage

4 °C

Storage Comment

Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Sancho, Ledbetter, Choi, Kanner, Deans, Terhorst: "CD3-zeta surface expression is required for CD4-p56lck-mediated upregulation of T cell antigen receptor-CD3 signaling in T cells." in: The Journal of biological chemistry, Vol. 267, Issue 11, pp. 7871-9, (1992) (PubMed).
Target

CD3

Alternative Name

CD3 (CD3 Products)

Synonyms

CD3 antibody, AI504783 antibody, CD3epsilon antibody, T3e antibody, cd3-gamma antibody, cd3g antibody, cd3g-a antibody, cd3g/d antibody, cd3gd antibody, t3g antibody, CD3e molecule antibody, CD3d molecule antibody, CD3 antigen, epsilon polypeptide antibody, CD3g molecule S homeolog antibody, CD3E antibody, CD3D antibody, Cd3e antibody, cd3g.S antibody

Background

Clone SP34 reacts with human form of the 20 kDa epsilon subunit of the CD3 antigen/T-cell receptor (TCR) complex. This clone also cross-reacts with a major subset of peripheral blood lymphocytes, but not monocytes or granulocytes, of rhesus or cynomolgus and pigtail macaque monkeys. The distribution on lymphocytes is similar to that observed with normal human donor lymphocytes, with the majority of CD3-positive cells being negative when dual stained with antibodies to B or NK cell markers.

Pathways

TCR Signaling, Ubiquitin Proteasome Pathway