CD3 antibody
(1 reference)-
- Target See all CD3 Antibodies
- CD3
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD3 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Functional Studies (Func)
- Brand
- BD Pharmingen™
- Purification
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
- Clone
- UCHT1
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product CD3 Primary Antibody
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anti-CD3 (CD3) antibody
CD3 Reactivity: Human, Mouse, Rat IHC, IF, WB Host: Rabbit Polyclonal unconjugated
anti-CD3 (CD3) antibodyCD3 Reactivity: Human, Non-Human Primate FACS, IP, IHC (fro), ICC, CyTOF Host: Mouse Monoclonal UCHT1 unconjugated
anti-CD3 (CD3) antibodyCD3 Reactivity: Human FACS, IP, CyTOF Host: Mouse Monoclonal MEM-57 unconjugated
anti-CD3 (CD3) antibodyCD3 Reactivity: Human FACS, IP, Func, CyTOF Host: Mouse Monoclonal MEM-57 unconjugated
anti-CD3 (CD3) antibodyCD3 Reactivity: Human, Non-Human Primate FACS, IP, IHC (fro), Func, CyTOF Host: Mouse Monoclonal UCHT1 unconjugated
anti-CD3 (CD3) antibody (Biotin)CD3 Reactivity: Human FACS, IP Host: Mouse Monoclonal MEM-57 Biotin
anti-CD3 (CD3) antibody (Biotin)CD3 Reactivity: Human, Non-Human Primate FACS, IP, IHC (fro) Host: Mouse Monoclonal UCHT1 Biotin
anti-CD3 (CD3) antibody (APC)CD3 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal UCHT1 APC
anti-CD3 (CD3) antibody (PerCP)CD3 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal UCHT1 PerCP
anti-CD3 (CD3) antibody (PE)CD3 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal UCHT1 PE
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/mL
- Buffer
- No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
- Preservative
- Azide free
- Storage
- 4 °C
- Storage Comment
- Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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: "Distinctive functional characteristics of human "T" lymphocytes defined by E rosetting or a monoclonal anti-T cell antibody." in: European journal of immunology, Vol. 11, Issue 4, pp. 329-34, (1981) (PubMed).
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: "Distinctive functional characteristics of human "T" lymphocytes defined by E rosetting or a monoclonal anti-T cell antibody." in: European journal of immunology, Vol. 11, Issue 4, pp. 329-34, (1981) (PubMed).
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- Target
- CD3
- Alternative Name
- CD3 (CD3 Products)
- Synonyms
- CD3 antibody, AI504783 antibody, CD3epsilon antibody, T3e antibody, cd3-gamma antibody, cd3g antibody, cd3g-a antibody, cd3g/d antibody, cd3gd antibody, t3g antibody, CD3e molecule antibody, CD3d molecule antibody, CD3 antigen, epsilon polypeptide antibody, CD3g molecule S homeolog antibody, CD3E antibody, CD3D antibody, Cd3e antibody, cd3g.S antibody
- Background
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The UCHT1 monoclonal antibody specifically binds to the human CD3epsilon-chain, a 20-kDa subunit of the CD3/T cell antigen receptor complex. CD3epsilon is expressed on 70-80% of normal human peripheral blood lymphocytes and 60-85% of thymocytes. Studies from the HLDA Workshop show that this antibody is mitogenic for CD3epsilon-positive cells when used in conjunction with costimulatory agents such as pokeweed mitogen or anti-CD28 antibody. CD3 plays a central role in signal transduction during antigen recognition. The UCHT1 antibody stains both surface and intracellular CD3epsilon unlike the other CD3 clone, HIT3a, that stains only extracellular CD3epsilon.
Synonyms: CD3e, CD3E, T3E, TCRE , T-cell surface antigen T3/Leu-4 epsilon - Pathways
- TCR Signaling, Ubiquitin Proteasome Pathway
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