Cyclin-Dependent Kinase Inhibitor 2D (p19, Inhibits CDK4) (CDKN2D) antibody

Details for Product No. ABIN119188
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Antigen
Synonyms ink4d, p19, p19-ink4d, CDKN2D, ank2, INK4D, p19-INK4D, INK4d, p19INK4d
Reactivity
Human
(53), (12), (12)
Host
Mouse
(29), (24)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Western Blotting (WB)
(30), (19), (13), (12), (10), (10), (7), (4), (4), (3), (2), (1)
Pubmed 1 reference available
Quantity 0.1 mg
Shipping to United States (Change)
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Request Want additional data for this product?

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Catalog No. ABIN119188
632.50 $
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Immunogen Full length recombinant p19-His tagged
Clone DCS-100-1
Isotype IgG1
Specificity This antibody recognises p19ink4d, a 19 kDa tumour suppressor protein which is a specific inhibitor of cdk4/cdk6. Clone DCS100.1 co-precipitates cdk4/cdk6 in immunoprecipitation studies.
Purification Affinity chromatography on Protein G
Alternative Name CDKN2D / p19INK4d
Background P19ink4d is periodically expressed during the cell cycle. Maximum induction of p19ink4d occurs as cells enter S phase.Synonyms: Cyclin-dependent kinase 4 inhibitor D, INK4D, p19, p19-INK4d
Gene ID 1032
NCBI Accession NP_001791
UniProt P55273
Application Notes Western Blot. Immunoprecipitation. Immunohistochemistry on frozen sections. Recommended Positive Control: Spleen.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 1.0 mg/mL IgG
Buffer PBS containing 0.08 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Hirai, Roussel, Kato et al.: "Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6." in: Molecular and cellular biology, Vol. 15, Issue 5, pp. 2672-81, 1995 (PubMed).

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