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Details for Product No. ABIN119188

Cyclin-Dependent Kinase Inhibitor 2D (p19, Inhibits CDK4) (CDKN2D) antibody

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Antigen
Synonyms p19, INK4D, p19-INK4D, INK4d, p19INK4d, ink4d, p19-ink4d, CDKN2D, ank2
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN119188
Quantity 0.1 mg
Price
621.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Immunogen Full length recombinant p19-His tagged
Clone DCS-100-1
Isotype IgG1
Specificity This antibody recognises p19ink4d, a 19kD tumour suppressor protein which is a specific inhibitor of cdk4/cdk6. Clone DCS100.1 co-precipitates cdk4/cdk6 in immunoprecipitation studies.
Purification Affinity chromatography on Protein G
Alternative Name CDKN2D / p19INK4d
Background P19ink4d is periodically expressed during the cell cycle. Maximum induction of p19ink4d occurs as cells enter S phase.
Alternate names: Cyclin-dependent kinase 4 inhibitor D, INK4D, p19, p19-INK4d
Gene ID 1032
NCBI Accession NP_001791.1
UniProt P55273
Application Notes Western Blot. Immunoprecipitation. Immunohistochemistry on frozen sections. Recommended Positive Control: Spleen. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL IgG
Buffer PBS containing 0.08% Sodium Azide
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Hirai, Roussel, Kato et al.: "Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6." in: Molecular and cellular biology, Vol. 15, Issue 5, pp. 2672-81, 1995 (PubMed).

Alternatives for antigen "Cyclin-Dependent Kinase Inhibitor 2D (p19, Inhibits CDK4) (CDKN2D)", type "Antibodies"
Hosts (25), (20)
Reactivities (46), (13), (12)
Applications (25), (14), (14), (13), (10), (7), (4), (4), (3), (2), (2), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (5), (1), (1), (1)
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