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CD46 antibody

CD46 Reactivity: Human WB, FACS, IP Host: Mouse Monoclonal MEM-258 unconjugated
Catalog No. ABIN119580
  • Target See all CD46 Antibodies
    CD46
    Reactivity
    • 117
    • 39
    • 20
    • 10
    • 10
    • 1
    Human
    Host
    • 84
    • 53
    • 2
    Mouse
    Clonality
    • 73
    • 66
    Monoclonal
    Conjugate
    • 52
    • 18
    • 16
    • 9
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD46 antibody is un-conjugated
    Application
    • 91
    • 80
    • 43
    • 40
    • 32
    • 19
    • 14
    • 14
    • 14
    • 10
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)
    Purification
    Affinity chromatography on Protein A
    Immunogen
    HPB-ALL cell line
    Clone
    MEM-258
    Isotype
    IgG1
    Top Product
    Discover our top product CD46 Primary Antibody
  • Application Notes
    Flow cytometry: 1/10 - 1/50, use 10 μL of the suggested working dilution to label 10^6 cells. Immunoprecipitation. Western Blot.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.09 % Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    CD46
    Alternative Name
    CD46 / MCP (CD46 Products)
    Synonyms
    AHUS2 antibody, MCP antibody, MIC10 antibody, TLX antibody, TRA2.10 antibody, Mcp antibody, CD46 antibody, CD46 molecule antibody, CD46 antigen, complement regulatory protein antibody, CD46 molecule, complement regulatory protein antibody, membrane cofactor protein-like antibody, CD46 antibody, Cd46 antibody, LOC100341359 antibody, LOC103789310 antibody
    Background
    CD46 functions as an inhibitor of complement activation limiting the formation and activity of C3 convertases. CD46 is expressed by all nucleated cells, often as multiple isoforms on the same cells. The molecule is also expressed by sperm and may be important in the process of fertilisation.Synonyms: MIC10, Membrane cofactor protein, TLX, Trophoblast leukocyte common antigen
    Gene ID
    9606
    UniProt
    P15529
    Pathways
    Regulation of Actin Filament Polymerization
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