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hCG antibody (Domain Holo C3)

hCG Reactivity: Human RIA, EIA Host: Mouse Monoclonal INN-hCG-45 unconjugated
Catalog No. ABIN120020
  • Target See all hCG Antibodies
    hCG (Chorionic Gonadotropin (hCG))
    Binding Specificity
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Domain Holo C3
    Reactivity
    • 31
    • 1
    • 1
    Human
    Host
    • 18
    • 5
    • 5
    • 3
    • 1
    Mouse
    Clonality
    • 18
    • 12
    Monoclonal
    Conjugate
    • 29
    • 3
    • 1
    This hCG antibody is un-conjugated
    Application
    • 20
    • 9
    • 8
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Radioimmunoassay (RIA), Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts with holo-hCG recognising the c3 epitope on hCG. No subunit detection is observed. Can be used in combination with INN-hCG-22 and 24. Suitable for use as a capture antibody.
    Purification
    Ion exchange on Protein A
    Immunogen
    Human CG.
    Clone
    INN-hCG-45
    Isotype
    IgG1
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  • Application Notes
    ELISA. Radioimmunoassays.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS pH 7.4 containing 0.09 % Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    hCG (Chorionic Gonadotropin (hCG))
    Abstract
    hCG Products
    Synonyms
    CGB antibody, AW108023 antibody, HCG antibody, chorionic gonadotropin, beta polypeptide antibody, ubiquitin-like 3 antibody, chorionic gonadotropin beta subunit 5 antibody, CGB antibody, Ubl3 antibody, CGB5 antibody
    Background
    Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced by trophoblastic cells of the placenta beginning 10 to 12 days after conception. Maintenance of the fetus in the first trimester of pregnancy requires the production of hCG, which binds to the corpus luteum of the ovary which is stimulated to produce progesterone which in turn maintains the secretory endometrium. hCG is present only in trace amounts in non pregnant urine and sera. It rises sharply during pregnancy. HCG is composed of two non identical, non covalently linked polypeptide chains designated as the a and b subunits. The a subunit of HCG is nearly identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH) and luteinizing hormone (LH). A germ cell tumor which is positive for cytokeratin, placental alkaline phosphatase (PLAP) and HCG but negative for EMA and AFP is probably a choriocarcinoma.Synonyms: CGB, CGB3, Choriogonadotropin subunit beta, beta hCG, hCG-beta
    Gene ID
    1082
    NCBI Accession
    NP_000728
    UniProt
    P01233
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