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SIRPA antibody (Biotin)
SIRPA
Reactivity: Rat
FACS
Host: Mouse
Monoclonal
OX-41
Biotin
Product Details anti-SIRPA Antibody (Biotin)
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Target
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SIRPA
(Signal-Regulatory Protein alpha (SIRPA))
Reactivity
All reactivities for SIRPA antibodies
Rat
Host
All hosts for SIRPA antibodies
Mouse
Clonality
All clonalities for SIRPA antibodies
Monoclonal
Conjugate
All conjugates for SIRPA antibodies
This SIRPA antibody is conjugated to Biotin
Application
All applications for SIRPA antibodies
Flow Cytometry (FACS)
Specificity
This antibody recognises rat CD172a, also known as Signal regulatory protein (SIRP). MRC OX-41 binds to a different epitope on SIRP than ED9.
Immunogen
Rat peritoneal macrophages. Spleen cells from immunised BALB/c mice were fused with the NSO/U mouse myeloma cell line.
Clone
OX-41
Isotype
IgG2a
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Alternatives
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Application Details
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Application Notes
Flow Cytometry. Immunohistochemistry on frozen and paraffin sections: This product requires protein digestion pre-treatment of paraffin sections e.g. trypsin or pronase. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Concentration
0.1 mg/mL
Buffer
Containing 0.09 % Sodium Azide and 1.0 % Bovine Serum Albumin
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for SIRPA
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Target
SIRPA
(Signal-Regulatory Protein alpha (SIRPA))
Alternative Name
CD172a / SIRPA (SIRPA Products )
Synonyms
BIT antibody, CD172A antibody, MFR antibody, MYD-1 antibody, P84 antibody, PTPNS1 antibody, SHPS1 antibody, SIRP antibody, SIRPA antibody, SIRP-A1 antibody, SIRP-B1 antibody, AI835480 antibody, Bit antibody, CD172a antibody, Ptpns1 antibody, SHP-1 antibody, SHPS-1 antibody, swc3 antibody, signal regulatory protein alpha antibody, myeloperoxidase antibody, signal-regulatory protein alpha antibody, tyrosine-protein phosphatase non-receptor type substrate 1 antibody, SIRPA antibody, MPO antibody, LOC458039 antibody, LOC100400378 antibody, LOC100590224 antibody, Sirpa antibody
Background
CD172a is expressed selectively by myeloid cells and by neurons.Synonyms: BIT, Brain Ig-like molecule with tyrosine-based activation motifs, CD172 antigen-like family member A, Inhibitory receptor SHPS-1, MFR, MYD1, Macrophage fusion receptor, MyD-1 antigen, PTPNS1, SHP substrate 1, SHPS-1, SHPS1, Signal-regulatory protein alpha-1, Sirp-alpha-2, Sirp-alpha-3, Tyrosine-protein phosphatase non-receptor type substrate 1, p84
Gene ID
25528
NCBI Accession
NP_037148
UniProt
P97710
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