Mouse anti-Human IgA (Secretory Component) Antibody

Details for Product No. ABIN120657, Supplier: Log in to see
Antigen
Epitope
Secretory Component
200
162
132
48
39
19
16
16
16
6
6
3
3
3
2
2
2
1
1
1
1
Reactivity
Human
767
194
122
76
48
48
38
36
36
34
27
23
14
13
7
5
4
3
3
3
2
1
1
1
Host
Mouse
758
314
277
42
37
12
9
Clonality (Clone)
Monoclonal ()
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
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Immunogen Affinity-purified secretory component from human colostrum
Clone SC-05
Isotype IgG1
Purification Affinity Chromatography on Protein A
Background Synonyms: Human Immunoglobulin A
Molecular Weight approx. 80 kDa
Research Area Immunology, Secondary Antibodies
Application Notes Immunoprecipitation. Western Blotting. Immunohistochemistry (paraffin sections). Immunohistochemistry (frozen sections). Examples of positive human tissues: secretory mucosa of gastrointestinal and respiratory tract, epithelia of salivary glands, endometrium, endocervix, kidney, prostate, mammary gland.

Other applications not tested.
Otimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 1.0 mg/mL
Buffer Tris buffered saline (TBS), pH ~8.0 with 15 mM Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Avoid freeze/thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -28 °C for longer.
Supplier Images
Immunohistochemistry (IHC) image for Mouse anti-Human IgA (Secretory Component) Antibody (ABIN120657) Formalin-fixed, paraffin-embedded human colon carcinoma stained with Secretory Compon...
Background publications Bártek, Tlaskalová-Hogenová, Stasková, Simecková, Vojt?sek, Rejthar, Kovarík, Bartková: "Secretory component in differentiating normal epithelium, benign lesions and malignancy in the human breast as monitored by monoclonal antibodies." in: Histochemistry, Vol. 91, Issue 3, pp. 235-44, 1989 (PubMed).

Kvale, Bartek, Sollid, Brandtzaeg: "Rapid selection of cultured cells with increased expression of a membrane marker (secretory component)." in: International journal of cancer. Journal international du cancer, Vol. 42, Issue 4, pp. 638-41, 1988 (PubMed).