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SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) antibody

Details for Product No. ABIN121150, Supplier: Log in to see
Antigen
  • KMT7
  • SET7
  • SET7/9
  • SET9
  • set7
  • zgc:101860
  • zgc:92330
  • 1600028F23Rik
  • H3K4MT
  • Set7
  • Set7/9
  • mKIAA1717
Reactivity
Human
85
25
21
2
2
1
1
1
1
1
1
1
1
Host
Mouse
58
27
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
62
34
19
13
11
8
7
3
3
3
Supplier
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Immunogen Recombinant human SET7/9 protein
Clone S4E5
Isotype IgG2b
Specificity The antibody recognizes Human SET7/9. Other species not tested.
Purification Affinity Chromatography on Protein G
Alternative Name SETD7 / SET9 (SETD7 Antibody Abstract)
Background Set7/9 is a histone methyltransferase (HMTase) that transfers methyl group to Lys4 of histone H3, in complex with S-adenosyl-L-methionine (AdoMet). The methylation of lysine residues of histones plays a critical role in the regulation of chromatin structure and gene expression. Acetylation, phosphorylation and methylation of the amino-terminal tails of histone are thought to be involved in the regulation of chromatin structure and function. The enzymes identified in the methylation of specific lysine residue on histones belong to the SET family with just one exception. Set7/9, unlike most other SET proteins, is exclusively a mono-methylase.Synonyms: H3-K4-HMTase SETD7, Histone H3-K4 methyltransferase SETD7, Histone-lysine N-methyltransferase SETD7, KIAA1717, KMT7, Lysine N-methyltransferase 7, SET domain-containing protein 7, SET7, SET7/9
Gene ID 80854
UniProt Q8WTS6
Application Notes ELISA. Western blot (1:250 - 1:2,000), recommended starting dilution : 1:1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative., 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.
Expiry Date 12 months
Supplier Images
 image for anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) antibody (ABIN121150) Immunoblot analysis.,.Recombinant SET7/9 was resolved by electrophoresis, transferred...
Background publications Nishioka, Chuikov, Sarma et al.: "Set9, a novel histone H3 methyltransferase that facilitates transcription by precluding histone tail modifications required for heterochromatin formation." in: Genes & development, Vol. 16, Issue 4, pp. 479-89, 2002 (PubMed).