TAS1R1
Reactivity: Human
WB, IF (cc), IF (p)
Host: Rabbit
Polyclonal
AbBy Fluor® 488
Application Notes
Immunohistochemistry with formalin fixed paraffin embedded tissues: 5 μg/mL. Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.
Restrictions
For Research Use only
Concentration
1.0 mg/mL
Buffer
PBS containing 0.09 % Sodium Azide as preservative.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 to -70 °C forlonger. Avoid repeated freezing and thawing. Shelf life: One year from despatch.
Expiry Date
12 months
Target
TAS1R1
(Taste Receptor, Type 1, Member 1 (TAS1R1))
GPR70 antibody, T1R1 antibody, TR1 antibody, Gpr70 antibody, T1r1 antibody, taste receptor, type 1, member 1 antibody, taste 1 receptor member 1 antibody, tas1r1 antibody, TAS1R1 antibody, Tas1r1 antibody
Background
TAS1R1 is a Taste Receptor, G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-enantiomers or other compounds. Most amino acids that are perceived as sweet activate T1R1+3, and this activation is strictly dependent on an intact T1R1+3 heterodimer. Multiple transcript variants encoding several different isoforms have been found for this gene. The expression of this gene is largely restricted to taste buds in mammals. However, some ESTs have been isolated from liver, testis and bone. TAS1R1 combines with TAS1R3 to function as an L-amino-acid receptor and is only activated by these sweet amino acids. ESTs have been isolated from testis libraries.Synonyms: G-protein coupled receptor 70, GM148, TR1, Taste receptor T1R1, Taste receptor type 1 member 1