GHSR antibody (Extracellular Domain, N-Term)

Catalog No. ABIN122500

Product Details anti-GHSR Antibody

Target: GHSR (Growth Hormone Secretagogue Receptor (GHSR))

Binding Specificity: Extracellular Domain, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GHSR antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Thia antibody reacts with Human Growth Hormone Secretagogue Receptor (GHSR) (family: GPCR, subfamily: Releasing hormone), N-terminal extracellular domain of human.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide (N-terminal extracellular domain) - KLH conjugated

Application Details

Application Notes: Immunohistochemistry on formalin fixed paraffin embedded tissues: 4 μg/mL. Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min, Remove from heat and let stand at room temperature in buffer for 20 min, Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International. Ligand: Ghrelin.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-80 °C

Storage Comment: Store the antibody at 2-8 °C for one month or at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: One year from despatch.

Expiry Date: 12 months

Target Details for GHSR

Target: GHSR (Growth Hormone Secretagogue Receptor (GHSR))

Alternative Name: Ghrelin Receptor / GHSR (GHSR Products)

Synonyms: GHSR antibody, C530020I22Rik antibody, growth hormone secretagogue receptor antibody, growth hormone secretagogue receptor,putative antibody, GHSR antibody, Smp_164730 antibody, Ghsr antibody

Background: Ghrelin is the endogenous ligand for the ghrelin receptor (GHSR). Accumulating evidence suggests that ghrelin may play a role in metabolism, body weight, feeding and adiposity. Ghrelin is also a hormone that stimulates growth hormone secretion and signals energy insufficiency via interaction with its receptor. The ghrelin receptor is located in both the central nervous system and the periphery. GHSR has been reported to be expressed primarily in brain and pituitary. Various other tissues, including colon, gastrointestinal tract, kidney, lung, placenta, stomach, thyroid, and vessel, express GHSR.Synonyms: GH-releasing peptide receptor, GHRP, Growth hormone secretagogue receptor type 1

Gene ID: 2693

UniProt: Q92847

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion, Feeding Behaviour