NAIP antibody

Catalog No. ABIN127053

The Rabbit Polyclonal anti-NAIP antibody (ABIN127053) specifically detects NAIP in WB. The antibody is reactive with Human samples.

Quick Overview for NAIP antibody (ABIN127053)

Target: NAIP (NLR Family, Apoptosis Inhibitory Protein (NAIP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NAIP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NAIP Antibody

Specificity: This antibody detects NAIP.

Purification: Affinity purified

Immunogen: Synthetic peptide surrounding amino acid 506 of human NAIP.

Application Details

Application Notes: Western Blot: 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: PBS, pH 7.2, containing 50 % glycerol, 1 % BSA, 0.02 % thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C/-80 °C

Storage Comment: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Target Details for NAIP

Target: NAIP (NLR Family, Apoptosis Inhibitory Protein (NAIP))

Alternative Name: NAIP

Background: NAIP (neuronal apoptosis inhibitor protein) is a member of the IAPs (inhibitor of apoptosis proteins) that function in cell death pathways to inhibit apoptosis. NAIP was discovered based on its association with a neurodegenerative disorder. Mutations and deletions in the NAIP gene locus is a contributing factor in spinal muscular atrophy. Coexpression of NAIP and hippocalcin protects neurons against calcium-induced cell death. NAIP is strongly expressed in anterior horn and motor cortex neurons of the normal brain. It is also found in human fetal neurons and in adult choroid plexus cells.Synonyms: BIRC1, Baculoviral IAP repeat-containing protein 1

Gene ID: 100510692

NCBI Accession: NP_004527

UniProt: Q13075

Pathways: Apoptosis, Inflammasome