BCMA antibody (C-Term)

Catalog No. ABIN127204

This Rabbit Polyclonal antibody specifically detects BCMA in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for BCMA antibody (C-Term) (ABIN127204)

Target: BCMA (TNFRSF17) (Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCMA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-BCMA Antibody

Binding Specificity: C-Term

Specificity: Detects 27 kDa human BCMA.

Purification: Affinity purified

Immunogen: Synthetic peptide mapping at the carboxy terminus of human BCMA.

Application Details

Application Notes: Western Blot: 2-6 μg/mL. Immunohistochemistry: 5-20 μg/mL. Human spleen tissue can be used as a positive control.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS, pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C/-80 °C

Storage Comment: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Target Details for BCMA

Target: BCMA (TNFRSF17) (Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))

Alternative Name: CD269 / BCMA

Background: BCMA is a recently identified receptor for BAFF. It binds BAFF and April. BAFF and its receptors induce B cell development and survival, activate NF-κB and c-Jun N-terminal kinase, and are involved in B cell associated autoimmune diseases.Synonyms: B-cell maturation protein, BCM, TNFRSF17, Tumor necrosis factor receptor superfamily member 17

Gene ID: 608

NCBI Accession: NP_001183

UniProt: Q02223