TNFRSF17
Reactivity: Human
WB, IP
Host: Rabbit
Polyclonal
unconjugated
Application Notes
WB (H) 1:250-1:500, IHC/IF (R) 1:600-1:1200
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS, pH 7.4, 0.02 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Target
BCMA (TNFRSF17)
(Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))
Alternative Name
BCMA
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.