TNFRSF17
Reactivity: Human
WB, IP
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Flow Cyt 1:100, IP 1:30
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Please see Certificate of Analysis for specific instructions of reconstitution.
Buffer
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Storage
-20 °C,-80 °C
Storage Comment
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C(Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Expiry Date
12 months
Target
BCMA (TNFRSF17)
(Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))
Alternative Name
BCMA
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.