CD81 antibody (PE)
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- Target See all CD81 Antibodies
- CD81
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Reactivity
- Mouse
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD81 antibody is conjugated to PE
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Application
- Flow Cytometry (FACS)
- Specificity
- Mouse CD81 (TAPA-1)
- Isotype
- IgG1
- Top Product
- Discover our top product CD81 Primary Antibody
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- Restrictions
- For Research Use only
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- Concentration
- 2.0 g/10 cells
- Buffer
- PE conjugated Ig buffered in PBS, 0.02% NaN and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
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- Target
- CD81
- Alternative Name
- CD81 (TAPA-1) (CD81 Products)
- Synonyms
- Tapa-1 antibody, Tapa1 antibody, Tspan28 antibody, CVID6 antibody, S5.7 antibody, TAPA1 antibody, TSPAN28 antibody, CD81 molecule antibody, CD81 molecule b antibody, CD81 antigen antibody, Cd81 molecule antibody, CD81 antibody, cd81b antibody, Cd81 antibody
- Background
- ABIN134046reacts with the extracellular loops of murine CD81 (TAPA- 1) molecule. As a member of the tetraspanin superfamily of cell-surface proteins, CD81 has been linked to the control of cell proliferation, adhesion and motility. CD81 is expressed in higher levels on resting murine B cells than on resting T cells and is functionally active on B cells as it induces homotypic adhesion of B lymphocytes. Unlike human CD81, which is expressed equally on all thymocytes, murine CD81 is upregulated on CD4 CD8 thymocytes, then down-regulated again on mature single-positive thymocytes. Murine dendritic cells, splenic macrophages and NK cells all express very high levels of CD81. CD81 has also been involved in the induction of IL-4 secretion from T cells during Th2 immune responses. It has been reported that CD81 expression can also be induced in mature T cells upon activation. This anti-CD81 mAb has been shown to decrease the proliferation of LPS stimulated CD81 +/+ B cells to levels similar to that of CD81 -/- B cells.
- Pathways
- Inositol Metabolic Process, Hepatitis C
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