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CD8 antibody (CD8a Molecule)

Details for Product anti-CD8A Antibody No. ABIN135734, Supplier: Log in to see
Antigen
  • BB154331
  • CD8
  • cd8
  • Leu2
  • LOC100136450
  • Ly-2
  • Ly-35
  • Ly-B
  • Lyt-2
  • MAL
  • p32
  • RHACD8-4
  • zgc:136643
Alternatives
anti-Human CD8 antibody for Immunohistochemistry (Frozen Sections)
Reactivity
Human
1058
532
167
68
47
40
25
22
20
20
19
16
15
13
12
12
11
11
10
10
8
8
5
3
3
2
2
2
2
1
1
1
Host
Mouse
1285
512
206
Clonality (Clone)
Monoclonal ()
Conjugate
This CD8 antibody is un-conjugated
259
217
142
86
52
42
40
39
30
30
29
28
27
26
25
25
25
25
25
21
21
18
18
17
11
10
10
10
8
6
6
5
4
4
4
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (IHC)
1617
452
355
343
285
282
255
238
214
37
33
25
23
17
14
10
7
6
6
6
5
4
4
4
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Supplier
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Clone RFT-8
Isotype IgG1
Characteristics The antibody detects: Human CD8
Purification Purified
Alternative Name CD8 (CD8A Antibody Abstract)
Background CD8 is a 32 kDa transmembrane glycoprotein expressed as either a CD8 homodimer or CD8 heterodimer. It is expressed on the cytotoxic/suppressor subpopulation of peripheral T cells. CD8 functions primarily as a coreceptor with MHC Class I-restricted TCR's in antigen recognition.
Research Area Immunology, Adaptive Immunity, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells
Pathways TCR Signaling
Application Notes Working Dilution:
FACS: 1 µg/10^6 cells
Representative data are included in this product insert.

Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Sample Volume 1 mL
Restrictions For Research Use only
Buffer Product is supplied as 0.1 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.0.
Preservative Azide free
Handling Advice Each reagent is stable for the period shown on the bottle label if stored as directed.
Storage 4 °C
Background publications Zamoyska: "The CD8 coreceptor revisited: one chain good, two chains better." in: Immunity, Vol. 1, Issue 4, pp. 243-6, 1995 (PubMed).