SCGN antibody (AA 221-276)

Catalog No. ABIN1386572

Product Details anti-SCGN Antibody

Target: SCGN (Secretagogin, EF-Hand Calcium Binding Protein (SCGN))

Binding Specificity: AA 221-276

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCGN antibody is un-conjugated

Application: ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Secretagogin

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for SCGN

Target: SCGN (Secretagogin, EF-Hand Calcium Binding Protein (SCGN))

Alternative Name: SCGN/Secretagogin (SCGN Products)

Synonyms: SCGN antibody, MGC146683 antibody, CALBL antibody, DJ501N12.8 antibody, SECRET antibody, SEGN antibody, setagin antibody, zgc:100843 antibody, secretagogin, EF-hand calcium binding protein antibody, Secretagogin antibody, secretagogin, EF-hand calcium binding protein L homeolog antibody, SCGN antibody, scgn antibody, segn antibody, scgn.L antibody, Scgn antibody

Background:

Synonyms: Calbindin like, CALBL, DJ501N12.8, Scgn, SECRET, Secretagogin, Secretagogin EF hand calcium binding protein, SEGN, SEGN_HUMAN, Setagin.

Background: SCGN is a 276 amino acid cytoplasmic protein that contains six EF-hand domains and is related to the calicium-binding proteins Calretinin and Calbindin D28K. Expressed in a variety of tissues including stomach, thyroid, colon, brain and neuroendocrine cells, SCGN is thought to be involved in cell proliferation and KCl (potassium chloride)-mediated calcium flux events. Through its interaction with KCl and its subsequent ability to modulate calcium storage pools within the cell, SCGN may function to negatively control growth and differentiation rates and, thus, indirectly inhibit cell replication.