TAS2R16 antibody (AA 147-182) (Biotin)
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- Target See all TAS2R16 Antibodies
- TAS2R16 (Taste Receptor, Type 2, Member 16 (TAS2R16))
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Binding Specificity
- AA 147-182
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TAS2R16 antibody is conjugated to Biotin
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Application
- Western Blotting (WB), ELISA
- Cross-Reactivity
- Human
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human TAS2R16
- Isotype
- IgG
- Top Product
- Discover our top product TAS2R16 Primary Antibody
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- Application Notes
- WB 1:300-5000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
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- Target
- TAS2R16 (Taste Receptor, Type 2, Member 16 (TAS2R16))
- Alternative Name
- TAS2R16 (TAS2R16 Products)
- Synonyms
- T2R16 antibody, Gm465 antibody, T2R18 antibody, Tas2r16 antibody, Tas2r18 antibody, mGR18 antibody, mt2r40 antibody, T2R3 antibody, taste 2 receptor member 16 antibody, taste receptor, type 2, member 118 antibody, TAS2R16 antibody, Tas2r118 antibody
- Background
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Synonyms: TAS2R-16, T2R16, Taste receptor type 2 member 16, T2R16_HUMAN.
Background: T2R16 is a 291 amino acid multi-pass membrane protein that belongs to the G-protein coupled receptor T2R family. Acting in the oral cavity and the gastrointestinal tract, T2R16 is a gustducin-coupled receptor that is implicated in the perception of bitter compounds. T2R16 mediates responses to certain taste through PLC 2, a phospholipase C selectively expressed in taste tissue, and the calcium-regulated cation channel TRPM5. Expressed in a subset of gustducin-positive taste receptor cells of the tongue and epithelia, T2R16 confers bitter perception of salicin to non-taster mice. The gene that encodes T2R16 consists of 996 bases and maps to human chromosome 7q31. Chromosome 7 houses over 1,000 genes, comprises nearly 5 % of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The Lys-172 polymorphism in T2R16 is associated with genetic susceptibility to alcoholism.
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