Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

INTS3 antibody (AA 960-998) (Alexa Fluor 350)

INTS3 Reactivity: Human, Mouse, Rat WB, IF (p) Host: Rabbit Polyclonal Alexa Fluor 350
Catalog No. ABIN1404537
  • Target See all INTS3 Antibodies
    INTS3 (Integrator Complex Subunit 3 (INTS3))
    Binding Specificity
    • 14
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 960-998
    Reactivity
    • 28
    • 19
    • 17
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 28
    Rabbit
    Clonality
    • 28
    Polyclonal
    Conjugate
    • 11
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This INTS3 antibody is conjugated to Alexa Fluor 350
    Application
    • 24
    • 12
    • 6
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human INTS3
    Isotype
    IgG
    Top Product
    Discover our top product INTS3 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    INTS3 (Integrator Complex Subunit 3 (INTS3))
    Alternative Name
    INTS3 (INTS3 Products)
    Synonyms
    INTS3 antibody, Ints3 antibody, NV18802 antibody, ACYPI009450 antibody, DL3335W antibody, FCAALL.260 antibody, embryo defective 2739 antibody, C1orf193 antibody, C1orf60 antibody, INT3 antibody, SOSS-A antibody, C77668 antibody, RGD1304593 antibody, si:dkey-27c15.2 antibody, integrator complex subunit 3 antibody, integrator complex subunit 3 L homeolog antibody, embryo defective 2739 antibody, INTS3 antibody, ints3.L antibody, CpipJ_CPIJ008133 antibody, ints3 antibody, Ints3 antibody, LOC100168776 antibody, emb2739 antibody
    Background

    Synonyms: INT3, SOSSA, SOSS-A, C1orf60, C1orf193, Integrator complex subunit 3, SOSS complex subunit A, Sensor of single-strand DNA complex subunit A, Sensor of ssDNA subunit A, INTS3

    Background: Component of the Integrator complex. The Integrator complex is involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. The SOSS complex is required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways. In the SOSS complex, it is required for the assembly of the complex and for stabilization of the complex at DNA damage sites.

    Gene ID
    65123
    UniProt
    Q68E01
You are here:
Support