HTR1F antibody (PE)

Catalog No. ABIN1429470

Product Details anti-HTR1F Antibody (PE)

Target: HTR1F (5-Hydroxytryptamine (serotonin) Receptor 1F (HTR1F))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HTR1F antibody is conjugated to PE

Application: Western Blotting (WB)

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human 5HT1F Receptor/SR-1F

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for HTR1F

Target: HTR1F (5-Hydroxytryptamine (serotonin) Receptor 1F (HTR1F))

Abstract: HTR1F Products

Synonyms: 5-HT-1F antibody, 5-HT1F antibody, 5HT6 antibody, HTR1EL antibody, MR77 antibody, Htr1eb antibody, 5htr1e antibody, 5htr1f antibody, 5-hydroxytryptamine receptor 1F antibody, 5-hydroxytryptamine (serotonin) receptor 1F antibody, uncharacterized LOC100406194 antibody, HTR1F antibody, Htr1f antibody, LOC100406194 antibody

Background:

Synonyms: 5 HT 1F, 5 HT1F, 5 hydroxytryptamine serotonin receptor 1F, 5 hydroxytryptamine 1F receptor, 5 hydroxytryptamine receptor 1E beta, 5 hydroxytryptamine receptor 1F, 5 hydroxytryptamine serotonin receptor 1E beta, 5 hydroxytryptamine serotonin receptor 1F, 5HT 1F, 5HT1F, HTR 1F, HTR1EB, HTR1EL, HTR1F, MR 77, MR77, Serotonin receptor 1E beta, Serotonin receptor gene, 5HT1F_HUMAN.

Background: The members of the G-protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. b-adrenergic bound to adrenaline activates adenylyl cyclase, while a2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. Like the a2-adrenergic receptor, serotonin receptor functions are also mediated by G proteins that inhibit the activity of adenylyl cyclase. The serotonin receptors have been classified into several categories, designated SR-17 (5HT17). Subtypes within the SR-1 group include SR-1A, -1B, -1D, -1E and -1F.

Pathways: JAK-STAT Signaling