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Mesothelin antibody
MSLN
Reactivity: Mouse
FACS
Host: Rat
Monoclonal
B35
unconjugated
Product Details anti-Mesothelin Antibody
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Target
See all Mesothelin (MSLN) Antibodies
Mesothelin (MSLN)
Reactivity
All reactivities for Mesothelin antibodies
Mouse
Host
All hosts for Mesothelin antibodies
Rat
Clonality
All clonalities for Mesothelin antibodies
Monoclonal
Conjugate
All conjugates for Mesothelin antibodies
This Mesothelin antibody is un-conjugated
Application
All applications for Mesothelin antibodies
Flow Cytometry (FACS)
Specificity
This antibody reacts with mouse mesothelin.
Purification
Protein G agarose
Immunogen
Murine hemangioblast-like cell line LO
Clone
B35
Isotype
IgG2a
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Discover our top product MSLN Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
1.0 mg/mL
Buffer
PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
Preservative
Without preservative
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Upon receipt, store (in aliqouts) at -20 °C.
Target Details for Mesothelin
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Target
Mesothelin (MSLN)
Alternative Name
Mesothelin (MSLN Products )
Synonyms
MPF antibody, SMRP antibody, MSLN antibody, mesothelin antibody, MSLN antibody, Msln antibody, LOC611363 antibody, LOC100524016 antibody
Background
Mesothelin (MSLN) is a GPI-linked cell surface glycoprotein expressed in the mesothelial lining of the body cavities and in mullerian duct epithelium related cancer cells (ovarian, pancreatic cancer, mesothelioma). Both human and mouse mesothelin bind to ovarian cancer antigen CA125/MUC16 with high affinity, mediating cell attachment in vitro , suggesting that mesothelin may facilitate ovarian cancer metastasis.Synonyms: CAK1 antigen, MPF, MSLN, Pre-pro-megakaryocyte-potentiating factor
Gene ID
56047
NCBI Accession
NP_061345
UniProt
Q61468
Pathways
EGFR Signaling Pathway , Positive Regulation of Peptide Hormone Secretion , Intracellular Steroid Hormone Receptor Signaling Pathway , Steroid Hormone Mediated Signaling Pathway , Carbohydrate Homeostasis , cAMP Metabolic Process , Regulation of G-Protein Coupled Receptor Protein Signaling , Positive Regulation of Endopeptidase Activity , Regulation of Carbohydrate Metabolic Process
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