ACER1 antibody (C-Term)

Catalog No. ABIN1449914

Product Details anti-ACER1 Antibody

Target: ACER1 (Alkaline Ceramidase 1 (ACER1))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACER1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VNAYALNSIA LHILYIVCQE YRKTSNKELR HLIEVSVVLW AVALTSWISD

Cross-Reactivity (Details): Species reactivity (expected):Dog, RabbitSpecies reactivity (tested):Human

Purification: Purified using peptide immunoaffinity column

Immunogen: Synthetic peptide directed towards the C terminal of human ACER1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Target Details for ACER1

Target: ACER1 (Alkaline Ceramidase 1 (ACER1))

Alternative Name: Alkaline Ceramidase 1 (ACER1 Products)

Synonyms: ASAH3 antibody, asah3 antibody, zgc:110285 antibody, ALKCDase1 antibody, 2310024P18Rik antibody, AI662009 antibody, Alkcdase1 antibody, Asah3 antibody, Cer1 antibody, alkaline ceramidase 1 antibody, ACER1 antibody, acer1 antibody, Acer1 antibody

Background: ACER1 hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 8.0. It has a highly restricted substrate specificity for the natural stereoisomer of ceramide with D-erythro-sphingosine but not D-ribo-phytosphingosine or D-erythro-dihydrosphingosine as a backbone. It may have a role in regulating the levels of bioactive lipids ceramide and sphingosine 1-phosphate, as well as complex sphingolipids.Synonyms: ACER1, ASAH3, Acylsphingosine deacylase 3, AlkCDase 1, Alkaline CDase 1, N-acylsphingosine amidohydrolase 3

Gene ID: 125981

NCBI Accession: NM_133492