RUTBC1 antibody, D630003G22Rik antibody, R74628 antibody, Rutbc1 antibody, mKIAA0397 antibody, small G protein signaling modulator 2 antibody, SGSM2 antibody, Sgsm2 antibody
Background
Small G proteins such as RAP and RAB proteins are the key molecules in intracellular signal transduction and vesicle transportation. A novel protein family small G protein signaling modulator (SGSM) consisting of three members SGSM1-3 bind to RAP and RAB family proteins. All three SGSM proteins possess both a RUN domain and a TBC domain. SGSM2 is a Rab9A effector that activates GTP hydrolysis by Rab32 and Rab33B proteins.Synonyms: RUTBC1, Small G protein signaling modulator 2