CASKIN1 antibody (Middle Region)

Catalog No. ABIN1449997

Product Details anti-CASKIN1 Antibody

Target: CASKIN1 (CASK Interacting Protein 1 (CASKIN1))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CASKIN1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Purification: Affinity chromatography purified via peptide column

Immunogen: A 17 amino acid synthetic peptide near the center of Human CASKIN1

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CASKIN1

Target: CASKIN1 (CASK Interacting Protein 1 (CASKIN1))

Alternative Name: CASKIN1 (CASKIN1 Products)

Synonyms: ANKS5A antibody, 3300002N10Rik antibody, C130061I24 antibody, C630036E02Rik antibody, mKIAA1306 antibody, CASK interacting protein 1 antibody, CASKIN1 antibody, Caskin1 antibody

Background: Calcium/calmodulin-dependent serine protein kinase (CASK) is a conserved multi-domain scaffolding protein involved in brain development, synapse formation, and establishment of cell polarity. CASKINs (CASK interacting proteins) interact with CASK and is thought to play a role in CASK function, specifically by coupling CASK to distinct downstream effectors. CASKIN1 is a multidomain protein containing six N-terminal ankyrin repeats, one SH3 domain, and two sterile alpha motif domains followed by a long proline-rich sequence and a short conserved C-terminal domain. CASKIN1 coassembles with CASK on the cytoplasmic tail of neurexin 1, suggesting that CASKIN and CASK coat the cytoplasmic tails of neurexins and other cell-surface proteins.Synonyms: ANKS5A, CASK interacting protein 1, Caskin-1

Molecular Weight: 157 kDa

Gene ID: 57524

NCBI Accession: NP_065815