NETO1 antibody (C-Term)

Catalog No. ABIN1450052

Product Details anti-NETO1 Antibody

Target: NETO1 (Neuropilin (NRP) and Tolloid (TLL)-Like 1 (NETO1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NETO1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse, Rat.

Purification: Affinity chromatography purified via peptide column

Immunogen: 18 amino acid synthetic peptide near the carboxy terminus of Human NETO1

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for NETO1

Target: NETO1 (Neuropilin (NRP) and Tolloid (TLL)-Like 1 (NETO1))

Alternative Name: NETO1 (NETO1 Products)

Synonyms: BCTL1 antibody, BTCL1 antibody, AI851453 antibody, Btcl1 antibody, C130005O10Rik antibody, RGD1566269 antibody, neuropilin and tolloid like 1 antibody, neuropilin (NRP) and tolloid (TLL)-like 1 antibody, NETO1 antibody, Neto1 antibody

Background: Neuropilin and tolloid-like protein 1 (NETO1) is involved in the development and/or maintenance of neuronal circuitry. It is a type I transmembrane protein that is expressed in the brain and retina. NETO1 contains one LDL-receptor class A domain and two CUB domains and is either membrane-bound or secreted. It has three alternatively spliced isoforms, the first two of which are retina-specific and the third of which is found in both retina and brain tissue. Furthermore, as an accessory subunit of the neuronal N-methyl-D-aspartate receptor (NMDAR), it regulates long-term NMDA receptor-dependent synaptic plasticity and cognition, at least in the context of spatial learning and memory.Synonyms: BTCL1, Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1, Neuropilin and tolloid-like protein 1

Gene ID: 81832

NCBI Accession: NP_694821

Pathways: Regulation of long-term Neuronal Synaptic Plasticity