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PSMC5 antibody (AA 127-406)

PSMC5 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3022098
  • Target See all PSMC5 Antibodies
    PSMC5 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 5 (PSMC5))
    Binding Specificity
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 127-406
    Reactivity
    • 28
    • 20
    • 19
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 22
    • 5
    • 1
    Rabbit
    Clonality
    • 21
    • 7
    Polyclonal
    Conjugate
    • 17
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PSMC5 antibody is un-conjugated
    Application
    • 17
    • 7
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (IF)
    Sequence
    LPNKVDPLVS LMMVEKVPDS TYEMIGGLDK QIKEIKEVIE LPVKHPELFE ALGIAQPKGV LLYGPPGTGK TLLARAVAHH TDCTFIRVSG SELVQKFIGE GARMVRELFV MAREHAPSII FMDEIDSIGS SRLEGGSGGD SEVQRTMLEL LNQLDGFEAT KNIKVIMATN RIDILDSALL RPGRIDRKIE FPPPNEEARL DILKIHSRKM NLTRGINLRK IAELMPGASG AEVKGVCTEA GMYALRERRV HVTQEDFEMA VAKVMQKDSE KNMSIKKLWK
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 127-406 of human PSMC5 (NP_002796.4).
    Isotype
    IgG
    Top Product
    Discover our top product PSMC5 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid freeze / thaw cycles
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    PSMC5 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 5 (PSMC5))
    Alternative Name
    PSMC5 (PSMC5 Products)
    Synonyms
    mSUG1 antibody, S8 antibody, SUG-1 antibody, SUG1 antibody, TBP10 antibody, TRIP1 antibody, p45 antibody, p45/SUG antibody, wu:fa14g03 antibody, wu:fb23a11 antibody, zgc:92464 antibody, sug-1 antibody, sug1 antibody, tbp10 antibody, Sug1 antibody, PSMC5 antibody, xsug1 antibody, protease (prosome, macropain) 26S subunit, ATPase 5 antibody, proteasome 26S subunit, ATPase 5 antibody, proteasome 26S subunit, ATPase 5 L homeolog antibody, proteasome 26S subunit, ATPase 5 S homeolog antibody, Psmc5 antibody, PSMC5 antibody, psmc5 antibody, psmc5.L antibody, psmc5.S antibody
    Background
    The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha. Two transcript variants encoding different isoforms have been found for this gene.,PSMC5,S8,SUG-1,SUG1,TBP10,TRIP1,p45,p45/SUG,ATPase 5,Cell Biology & Developmental Biology,Ubiquitin,PSMC5
    Molecular Weight
    44 kDa/45 kDa
    Gene ID
    5705
    UniProt
    P62195
    Pathways
    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
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