PSMC5 antibody (C-Term)

Catalog No. ABIN925894

Product Details anti-PSMC5 Antibody

Target: PSMC5 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 5 (PSMC5))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Zebrafish (Danio rerio), Dog, Pig, Xenopus laevis, Drosophila melanogaster, C. elegans

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMC5 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Dog (Canine), Caenorhabditis elegans (C. elegans), Fruit Fly (Drosophila melanogaster), Zebrafish (Brachydanio rerio), Frog, Cow (Bovine), Pig (Porcine)

Immunogen: PSMC5 antibody was raised in rabbit using the C terminal of PSMC5 as the immunogen

Application Details

Application Notes: WB: 1.25 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

PSMC5 Blocking Peptide, catalog no. 33R-1153, is also available for use as a blocking control in assays to test for specificity of this PSMC5 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for PSMC5

Target: PSMC5 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 5 (PSMC5))

Alternative Name: PSMC5 (PSMC5 Products)

Synonyms: mSUG1 antibody, S8 antibody, SUG-1 antibody, SUG1 antibody, TBP10 antibody, TRIP1 antibody, p45 antibody, p45/SUG antibody, wu:fa14g03 antibody, wu:fb23a11 antibody, zgc:92464 antibody, sug-1 antibody, sug1 antibody, tbp10 antibody, Sug1 antibody, PSMC5 antibody, xsug1 antibody, protease (prosome, macropain) 26S subunit, ATPase 5 antibody, proteasome 26S subunit, ATPase 5 antibody, proteasome 26S subunit, ATPase 5 L homeolog antibody, proteasome 26S subunit, ATPase 5 S homeolog antibody, Psmc5 antibody, PSMC5 antibody, psmc5 antibody, psmc5.L antibody, psmc5.S antibody

Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits.PSMC5 is one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha. Synonyms: Polyclonal PSMC5 antibody, Anti-PSMC5 antibody, proteasome, prosome, macropain 26S subunit, ATPase, 5 antibody.

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway