CBL antibody (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence) (AA 666-715)

Details for Product anti-CBL Antibody No. ABIN1526318, Supplier: Log in to see
Antigen
  • 4732447J05Rik
  • Cbl-2
  • c-Cbl
  • cbl
  • C-CBL
  • CBL2
  • FRA11B
  • NSLL
  • RNF55
  • c-cbl-like
  • RGD1561386
  • Casitas B-lineage lymphoma
  • Cbl proto-oncogene, E3 ubiquitin protein ligase
  • Cbl
  • CBL
Alternatives
anti-Human CBL antibody for Western Blotting
Epitope
AA 666-715, pTyr700
44
44
28
28
19
6
5
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
281
172
162
7
6
4
4
3
3
1
1
1
Host
Rabbit
224
46
16
1
Clonality
Polyclonal
Conjugate
This CBL antibody is un-conjugated
7
7
7
7
6
5
5
5
5
5
5
5
5
5
4
2
2
Application
Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
199
78
74
65
63
50
20
17
11
6
5
3
3
3
1
1
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Immunogen The antiserum was produced against synthesized peptide derived from human CBL around the phosphorylation site of Tyr700.
Isotype IgG
Specificity

CBL (Phospho-Tyr700) Antibody detects endogenous levels of CBL only when phosphorylated at Tyr700.

PhosphorylationH:Y700 M:Y698 R:Y806

Purification The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Purity > 95 %
Alternative Name CBL (CBL Antibody Abstract)
Background

Synonyms: Cas-Br-M (murine) ecotropic retroviral transforming, CBL E3 ubiquitin protein ligase, CBL2, Proto-oncogene c-CBL, Signal transduction protein CBL

NCBI Gene Symbol: CBL

Molecular Weight 99 kDa
Gene ID 867
OMIM 165360
UniProt P22681
Research Area Cancer, Transcription Factors, Proteolysis / Ubiquitin
Pathways TCR Signaling, Interferon-gamma Pathway, EGFR Signaling Pathway, EGFR Downregulation, VEGFR1 Specific Signals
Application Notes WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:1000
Comment

Unigene-Number: Hs.504096 (NCBI Gene Symbol: CBL)

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Stable at -20°C for at least 1 year.
Expiry Date 12 months
Supplier Images
Western Blotting (WB) image for anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) (pTyr700), (AA 666-715) antibody (ABIN1526318) Western blot analysis of extracts from K562 cells treated with Na3VO4 0.3nM, using CB...
Immunohistochemistry (IHC) image for anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) (pTyr700), (AA 666-715) antibody (ABIN1526318) Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using CBL ...
Immunofluorescence (IF) image for anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) (pTyr700), (AA 666-715) antibody (ABIN1526318) Immunofluorescence analysis of HepG2 cells, using CBL (Phospho-Tyr700) Antibody. The ...
Background publications Joazeiro, Wing, Huang, Leverson, Hunter, Liu: "The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase." in: Science (New York, N.Y.), Vol. 286, Issue 5438, pp. 309-12, 1999 (PubMed).

Did you look for something else?