Ifi1 antibody, Iigp3 antibody, Iipg3 antibody, Irgm antibody, LRG-47 antibody, IFI1 antibody, IRGM1 antibody, LRG47 antibody, immunity-related GTPase family M member 1 antibody, immunity-related GTPase M antibody, immunity related GTPase M antibody, immunity-related GTPase family M protein antibody, Irgm1 antibody, Irgm antibody, IRGM antibody, LOC481473 antibody
Background
Putative GTPase which is required for IFNG-mediated clearance of acute protozoan and bacterial infections. Functions in innate immune response probably through regulation of autophagy. May regulate proinflammatory cytokine production and prevent endotoxemia upon infection. Required for macrophage motility and possibly also for adhesion.