INA antibody (AA 100-150)

Catalog No. ABIN1574097

Product Details anti-INA Antibody

Target: INA (Internexin Neuronal Intermediate Filament Protein, alpha (INA))

Binding Specificity: AA 100-150

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Rabbit Anti-Alpha Internexin Polyclonal Antibody detects endogenous levels of human, mouse, and rat Alpha Internexin protein.

Purification: Immunoaffinity chromatography

Immunogen: KLH-coupled synthetic peptide within AA 100-150 of human Alpha Internexin

Isotype: IgG

Application Details

Application Notes: Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.

ELISA: 0.05-0.2 µg/mL
Western blot: 0.5-1 µg/mLOther Applications: user-optimized

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.4, containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Storage: 4 °C/-20 °C

Storage Comment: The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.

Target Details for INA

Target: INA (Internexin Neuronal Intermediate Filament Protein, alpha (INA))

Alternative Name: Alpha Internexin (INA Products)

Synonyms: NEF5 antibody, NF-66 antibody, TXBP-1 antibody, Inexa antibody, Intlaa antibody, Nf66 antibody, AV028420 antibody, NF66 antibody, ina-A antibody, xefiltin antibody, ina-a antibody, inexa antibody, MGC82496 antibody, INA antibody, si:ch211-67n3.6 antibody, nef5 antibody, xina antibody, nf-66 antibody, txbp-1 antibody, MGC69277 antibody, gefiltin antibody, zgc:110516 antibody, internexin neuronal intermediate filament protein alpha antibody, internexin neuronal intermediate filament protein, alpha antibody, internexin neuronal intermediate filament protein alpha S homeolog antibody, low molecular weight neuronal intermediate filament S homeolog antibody, internexin neuronal intermediate filament protein, alpha a antibody, internexin neuronal intermediate filament protein, alpha b antibody, INA antibody, Ina antibody, ina.S antibody, nif.S antibody, inaa antibody, ina antibody, inab antibody

Background: Alpha internexin (Neurofilament-66) is a class IV neuronal intermediate filament that is able to self-assemble. Being involved in the morphogenesis of neurons, it may form an independent structural network without the involvement of other neurofilaments. It may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross bridges.Rabbit Anti-Alpha Internexin Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide within residues 100-150 of human Alpha Internexin (Swiss Prot: Q16352).