BMP2 antibody

Catalog No. ABIN1589877

Product Details anti-BMP2 Antibody

Target: BMP2 (Bone Morphogenetic Protein 2 (BMP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Recombinant human BMP-2

Characteristics: Chromosomal location: 20p12
Anti-human BMP-2/4 polyclonal serum was produced from sera of rabbits pre- immunized with a highly purified synthetic peptide of the human BMP-2/4 sequence (C-terminal amino acids “C(SH)-L-D-E-Y-D-K-V-V-L-K-N-Y-Q-E-M-V-V-E-G“).

Purification: Anti-human BMP-2/4 polyclonal antiserum was purified by Protein A chromatography.

Isotype: IgG

Application Details

Application Notes: Western Blot: use 2-5 µg/mL

Comment:

Rabbit IG Polyclonal Antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS

Handling Advice: Centrifuge vial prior to opening.

Storage: -20 °C

Storage Comment: The lyophilized antibody is stable at room temperature for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 °C. Frozen aliquots are stable for at least 6 months when stored at -20 °C

Expiry Date: 6 months

Target Details for BMP2

Target: BMP2 (Bone Morphogenetic Protein 2 (BMP2))

Alternative Name: BMP-2 (BMP2 Products)

Synonyms: BDA2 antibody, BMP2A antibody, AI467020 antibody, Bmp2a antibody, BMP-2 antibody, xBMP-2 antibody, xbmp2 antibody, BMP2 antibody, bmp2a antibody, bmp2 antibody, wu:fc59d09 antibody, bone morphogenetic protein 2 antibody, bone morphogenetic protein 2 L homeolog antibody, Bone morphogenetic protein 2 antibody, bone morphogenetic protein 2a antibody, BMP2 antibody, Bmp2 antibody, bmp2.L antibody, bmp2 antibody, bmp2a antibody

Background: Human Bone Morphogenetic Protein-2 (BMP-2) is a disulfide-bonded homodimeric protein with an apparent molecular weight of 26 kDa. BMP-2 regulates similarly to its nearest homologue BMP-4 diverse fundamental processes during embryonic development: BMP-2 and other BMP proteins have great potential for medical therapeutic applications, in particular because they allow or at least accelerate the ossification of extensive bone lesions. The amino acid sequence of recombinant human BMP-2 starts with MQAKHKQ (position 283) containing the Met from the E. coli expression vector. The antibody cross-reacts displays cross-reaction with human BMP-4 monomers in Western Blot.
Synonyms: bone morphogenetic protein 2, BDA2, BMP2A, bone morphogenetic protein 4, ZYME, BMP2B, OFC11, BMP2B1, MCOPS6

NCBI Accession: NM_001200, NP_001191

UniProt: P12643

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Growth Factor Binding, Positive Regulation of fat Cell Differentiation