Stargazin antibody (AA 203-323)
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- Target See all Stargazin (CACNG2) Antibodies
- Stargazin (CACNG2) (Calcium Channel, Voltage-Dependent, gamma Subunit 2 (CACNG2))
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Binding Specificity
- AA 203-323
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Reactivity
- Rat
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Stargazin antibody is un-conjugated
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Application
- Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Specificity
- Detects ~35-55 kDa. Does not cross-react with TARPGamma3.
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Protein G Purified
- Immunogen
- Fusion protein amino acids 203-323 (Cytoplasmic C-terminus) of rat TARPGamma2
- Clone
- S245-36
- Isotype
- IgG2a
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- Application Notes
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- WB (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
- Comment
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1 μg/ml of ABIN1686631 was sufficient for detection of TARP Gamma2/4/8 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- -20°C
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Coexpressed auxiliary subunits exhibit distinct modulatory profiles on AMPA receptor function." in: Neuron, Vol. 83, Issue 3, pp. 601-15, (2014) (PubMed).
: "
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Coexpressed auxiliary subunits exhibit distinct modulatory profiles on AMPA receptor function." in: Neuron, Vol. 83, Issue 3, pp. 601-15, (2014) (PubMed).
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- Target
- Stargazin (CACNG2) (Calcium Channel, Voltage-Dependent, gamma Subunit 2 (CACNG2))
- Alternative Name
- Stargazin (CACNG2 Products)
- Synonyms
- cacng2 antibody, zgc:64200 antibody, CACNG2 antibody, stargazin antibody, AW060990 antibody, B230105C07Rik antibody, B930041E13Rik antibody, stargazer antibody, stg antibody, wag antibody, waggler antibody, Ipr328 antibody, MRD10 antibody, calcium voltage-gated channel auxiliary subunit gamma 2 antibody, calcium channel, voltage-dependent, gamma subunit 2a antibody, calcium channel, voltage-dependent, gamma subunit 2 antibody, CACNG2 antibody, cacng2a antibody, cacng2 antibody, Cacng2 antibody
- Background
- Stargazin belongs to a group called voltage gated calcium channels (VGCCs) which are present in most excitable cells. Stargazin is thought to stabilize the calcium channel in an inactivated (closed) state. There are five high voltage activated calcium channel types (L, N, P, Q, and R) and one low voltage activated channel type (T). Each of these channels exists as a heteromultimer of a1, b, a2/ d and g subunits with the voltage activated calcium channel function carried by the a subunits. VGCCs exert spatial and temporal control over cellular calcium concentrations and serve to modulate neurotransmitter release, hormone secretion, muscle contraction, electrical activity, cell metabolism and proliferation, gene expression, and neuronal survival.
- Gene ID
- 84347
- NCBI Accession
- NP_445803
- UniProt
- Q71RJ2
- Pathways
- Skeletal Muscle Fiber Development
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