IRF6 antibody (Cy7)
-
- Target See all IRF6 Antibodies
- IRF6 (Interferon Regulatory Factor 6 (IRF6))
-
Reactivity
- Human, Mouse, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This IRF6 antibody is conjugated to Cy7
-
Application
- Western Blotting (WB)
- Cross-Reactivity
- Human, Mouse
- Predicted Reactivity
- Rat,Cow,Sheep,Pig,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human IRF6
- Isotype
- IgG
- Top Product
- Discover our top product IRF6 Primary Antibody
-
-
- Application Notes
- IF(IHC-P) 1:50-200
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
-
- Target
- IRF6 (Interferon Regulatory Factor 6 (IRF6))
- Alternative Name
- Irf6 (IRF6 Products)
- Synonyms
- IRF6 antibody, lps antibody, pit antibody, pps antibody, vws antibody, ofc6 antibody, xIRF-6 antibody, DKFZp469E012 antibody, LPS antibody, OFC6 antibody, PIT antibody, PPS antibody, PPS1 antibody, VWS antibody, VWS1 antibody, zgc:63500 antibody, AI876454 antibody, E230028I05Rik antibody, mirf6 antibody, interferon regulatory factor 6 antibody, interferon regulatory factor 6 S homeolog antibody, IRF6 antibody, irf6 antibody, irf6.S antibody, Irf6 antibody
- Background
-
Synonyms: Interferon regulatory factor 6, IRF 6, IRF-6, IRF6, IRF6_HUMAN, LPS, OFC 6, OFC6, OTTHUMP00000034677, OTTHUMP00000034678, PIT, PPS, PPS1, VWS, VWS1.
Background: Interferon regulatory factor-1 (IRF-1) and IRF-2 have been identified as novel DNA-binding factors that function as regulators of both type I interferon (interferon-alpha and beta) and interferon-inducible genes. The two factors are structurally related, particularly in their N-terminal regions, which confer DNA binding specificity. In addition, both bind to the same sequence within the promoters of interferon-alpha and interferon-beta genes. IRF-1 functions as an activator of interferon transcription, while IRF-2 binds to the same cis elements and represses IRF-1 action. IRF-1 and IRF-2 have been reported to act in a mutually antagonistic manner in regulating cell growth, overexpression of the repressor IRF-2 leads to cell transformation while concomitant overexpression of IRF-1 causes reversion. IRF-1 and IRF-2 are members of a larger family of DNA binding proteins that includes IRF-3, IRF-4, IRF-5, IRF-6, IRF-7, ISGF-3 gamma p48 and IFN consensus sequence-binding protein (ICSBP).
-