CDX4 antibody (AA 185-284) (HRP)
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- Target See all CDX4 products
- CDX4 (Caudal Type Homeobox 4 (CDX4))
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Binding Specificity
- AA 185-284
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CDX4 antibody is conjugated to HRP
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Application
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Predicted Reactivity
- Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human CDX4
- Isotype
- IgG
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- Application Notes
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IHC-P 1:200-400
IHC-F 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handling Advice
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- CDX4 (Caudal Type Homeobox 4 (CDX4))
- Alternative Name
- CDX4 (CDX4 Products)
- Synonyms
- Xcad3 antibody, Xcad-3 antibody, Xtcad3 antibody, MGC68909 antibody, MGC130769 antibody, CDXB antibody, CDX4 antibody, CHUNP6923 antibody, cad1 antibody, cb546 antibody, cdx1 antibody, id:ibd1215 antibody, id:ibd2812 antibody, id:ibd5107 antibody, kgg antibody, kugelig antibody, Cdx-3 antibody, Cdx-4 antibody, Cdx3 antibody, RGD1561529 antibody, cad3 antibody, cdx4 antibody, caudal type homeobox 4 antibody, caudal type homeo box 4 antibody, caudal type homeobox 4 L homeolog antibody, CDX4 antibody, cdx4 antibody, Cdx4 antibody, cdx4.L antibody
- Background
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Synonyms: Caudal-type homeobox protein 4, CDX4, CDX4_HUMAN, Homeobox protein CDX-4.
Background: Cdx1, Cdx2 and Cdx4 are members of the caudal-type homeobox family of genes, which are homologs of the Drosophila caudal? gene required for anterior-posterior regional identity. The proteins encoded by these genes are transcription factors which play an important role in development by regulating the expression of Hox genes. Hox genes play a fundamental role in the development of the vertebrate central nervous system, heart, axial skeleton, limbs, gut, urogenital tract and external genitalia. Cdx4 is a major positive regulator of the expression of all Hox family members. Due to its critical role as a regulator, Cdx4 is a direct target of the canonical Wnt pathway. The loss of Cdx4 can result in the development of an expanded hindbrain, while the overexpression of Cdx4 may cause the hindbrain to lose its distinct segmental features and resemble the spinal cord.
- Gene ID
- 1046
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