APOA5 antibody
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- Target See all APOA5 Antibodies
- APOA5 (Apolipoprotein A-V (APOA5))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This APOA5 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
- Purification
- purified
- Immunogen
- Purified recombinant fragment of human Apoa5 expressed in E. coli.
- Clone
- 2G1H11
- Isotype
- IgG1
- Top Product
- Discover our top product APOA5 Primary Antibody
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- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS containing 0.03 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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The human apolipoprotein AV gene is regulated by peroxisome proliferator-activated receptor-alpha and contains a novel farnesoid X-activated receptor response element." in: The Journal of biological chemistry, Vol. 278, Issue 28, pp. 25468-80, (2003) (PubMed).
: "An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing." in: Science (New York, N.Y.), Vol. 294, Issue 5540, pp. 169-73, (2001) (PubMed).
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The human apolipoprotein AV gene is regulated by peroxisome proliferator-activated receptor-alpha and contains a novel farnesoid X-activated receptor response element." in: The Journal of biological chemistry, Vol. 278, Issue 28, pp. 25468-80, (2003) (PubMed).
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- Target
- APOA5 (Apolipoprotein A-V (APOA5))
- Alternative Name
- APOA5 (APOA5 Products)
- Synonyms
- APOAV antibody, RAP3 antibody, 1300007O05Rik antibody, Apoav antibody, apo-AV antibody, apoA-V antibody, APOA5 antibody, MGC140487 antibody, rap3 antibody, apoav antibody, apoa-v antibody, apolipoprotein A5 antibody, apolipoprotein A-V antibody, apolipoprotein A5 L homeolog antibody, APOA5 antibody, Apoa5 antibody, apoa5.L antibody, apoa5 antibody
- Background
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Description: Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglycerides, whereas a knock-in model with human ApoA5 produced 50-70 % lower concentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor- agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Despite these compelling molecular biology data, relatively little is known about ApoA5 protein in human serum. This antibody pair detected recombinant apoa5 protein in sandwich ELISA format and could be potential reagents for the development of clinical diagnostic kits.
Aliases: RAP3, APOAV, APOA-V, MGC126836, MGC126838
- Gene ID
- 116519
- HGNC
- 116519
- Pathways
- Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism
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