TGFBR3 antibody (AA 147-328)
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- Target See all TGFBR3 Antibodies
- TGFBR3 (Transforming Growth Factor, beta Receptor III (TGFBR3))
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Binding Specificity
- AA 147-328
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Reactivity
- Human, Mouse
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This TGFBR3 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purification
- purified
- Immunogen
- Purified recombinant fragment of human TGFBR3 (AA: 147-328 ) expressed in E. coli.
- Clone
- 1C5H11
- Isotype
- IgG1
- Top Product
- Discover our top product TGFBR3 Primary Antibody
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- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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The type III transforming growth factor-? receptor inhibits proliferation, migration, and adhesion in human myeloma cells." in: Molecular biology of the cell, Vol. 22, Issue 9, pp. 1463-72, (2011) (PubMed).
: "[Defective expression of TGFBR3 gene and its molecular mechanisms in non-small cell lung cancer cell lines]." in: Zhongguo fei ai za zhi = Chinese journal of lung cancer, Vol. 13, Issue 5, pp. 451-7, (2010) (PubMed).
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The type III transforming growth factor-? receptor inhibits proliferation, migration, and adhesion in human myeloma cells." in: Molecular biology of the cell, Vol. 22, Issue 9, pp. 1463-72, (2011) (PubMed).
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- Target
- TGFBR3 (Transforming Growth Factor, beta Receptor III (TGFBR3))
- Alternative Name
- TGFBR3 (TGFBR3 Products)
- Synonyms
- TGFBR3 antibody, DKFZp469I0915 antibody, BGCAN antibody, betaglycan antibody, 1110036H20Rik antibody, AU015626 antibody, AW215636 antibody, TBRIII antibody, transforming growth factor beta receptor 3 antibody, transforming growth factor, beta receptor III antibody, TGFBR3 antibody, tgfbr3 antibody, Tgfbr3 antibody
- Background
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Description: This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. , ,
Aliases: BGCAN, betaglycan
- Molecular Weight
- 93.4 kDa
- Gene ID
- 7049
- HGNC
- 7049
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