AIRE antibody (Internal Region)
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- Target See all AIRE Antibodies
- AIRE (Autoimmune Regulator (AIRE))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Rat, Dog, Cow
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Host
- Goat
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Clonality
- Polyclonal
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Conjugate
- This AIRE antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificity
- Reacts with human AIRE
- Cross-Reactivity
- Cow (Bovine), Dog (Canine), Rat (Rattus)
- Cross-Reactivity (Details)
- This antibody is expected to recognise isoform 1 (NP_000374.1) only. Cross reacts with bovine, canine and rat protein.
- Purification
- Antigen affinity purified
- Immunogen
- Synthetic peptide C-KDVDLSQPRKGRKP from an internal region of human AIRE (NP_000374.1). Percent identity with other species by BLAST analysis: Human (100%), Gorilla (100%), Rat (100%), Horse (100%), Dog (100%), Hamster (100%), Elephant (100%)
- Top Product
- Discover our top product AIRE Primary Antibody
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- Application Notes
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Working dilution: ELISA (1:32000), IHC-P (2.5 μg/mL), WB (0.5 - 1 μg/mL)
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- TBS, pH 7.3, BSA 0.5 % , Sodium azide 0.02 %
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Minimize freezing and thawing.
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- Target
- AIRE (Autoimmune Regulator (AIRE))
- Alternative Name
- AIRE (AIRE Products)
- Synonyms
- AIRE1 antibody, APECED antibody, APS1 antibody, APSI antibody, PGA1 antibody, autoimmune regulator antibody, autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) antibody, AaeL_AAEL013794 antibody, CpipJ_CPIJ001208 antibody, CpipJ_CPIJ001209 antibody, AIRE antibody, Aire antibody
- Background
- Transcriptional regulator that binds to DNA as a dimer or as a tetramer, but not as a monomer. Binds to G-doublets in an A/T-rich environment, the preferred motif is a tandem repeat of 5'-. ATTGGTTA-3' combined with a 5'-TTATTA-3' box. Binds to nucleosomes
- UniProt
- O43918
- Pathways
- Chromatin Binding
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