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BACE1 antibody (Internal Region)

BACE1 Reactivity: Human IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1732171
  • Target See all BACE1 Antibodies
    BACE1 (Beta-secretase 1 (BACE1))
    Binding Specificity
    • 16
    • 13
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 81
    • 52
    • 41
    • 7
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 76
    • 10
    Rabbit
    Clonality
    • 72
    • 14
    Polyclonal
    Conjugate
    • 55
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BACE1 antibody is un-conjugated
    Application
    • 63
    • 36
    • 29
    • 17
    • 14
    • 13
    • 13
    • 10
    • 10
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    Reacts with human BACE1
    Cross-Reactivity (Details)
    BLAST analysis of the peptide immunogen showed no homology with other human proteins.
    Purification
    Antigen affinity purified
    Immunogen
    Synthetic 15 amino acid peptide from internal region of human BACE1. Percent identity with other species by BLAST analysis: Human (100%), Gibbon (100%), Monkey (100%), Marmoset (100%), Mouse (100%), Rat (100%), Dog (100%), Bat (100%), Bovine (100%), ...
    Isotype
    IgG
    Top Product
    Discover our top product BACE1 Primary Antibody
  • Application Notes

    Working dilution: IHC - P (2.5 μg/mL)

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS, Sodium azide 0.1 %
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-80 °C
    Storage Comment
    Long term: -70°C, Short term: +4°C
  • Target
    BACE1 (Beta-secretase 1 (BACE1))
    Alternative Name
    BACE1 (BACE1 Products)
    Synonyms
    ASP2 antibody, BACE antibody, HSPC104 antibody, C76936 antibody, Bace antibody, MGC145931 antibody, BACE1 antibody, zgc:77409 antibody, beta-secretase 1 antibody, beta-site APP cleaving enzyme 1 antibody, beta-site APP-cleaving enzyme 1 antibody, BACE1 antibody, Bace1 antibody, bace1 antibody
    Background
    Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
    UniProt
    P56817
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