TRIM22 antibody

Catalog No. ABIN375357

Product Details anti-TRIM22 Antibody

Target: TRIM22 (Tripartite Motif Containing 22 (TRIM22))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM22 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity: Reacts with human 57 kDa Staf-50

Cross-Reactivity (Details): May cross react with proteins from other species due to sequence homology

Purification: Antiserum

Immunogen: Synthetic peptide derived from an internal domain of human TRIM22

Isotype: IgG

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- IHC : 1/50 to 1/500 - WB : 1/200 to 1/2 000

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Storage: 4 °C/-20 °C

Storage Comment: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 24 months

Target Details for TRIM22

Target: TRIM22 (Tripartite Motif Containing 22 (TRIM22))

Alternative Name: E3 Ubiquitin-Protein Ligase TRIM22 (TRIM22 Products)

Synonyms: GPSTAF50 antibody, RNF94 antibody, STAF50 antibody, tripartite motif containing 22 antibody, TRIM22 antibody

Background: Interferon-induced antiviral protein involved in cell innate immunity. The antiviral activity could in part be mediated by TRIM22-dependent ubiquitination of viral proteins. Plays a role in restricting the replication of HIV-1, encephalomyocarditis virus (EMCV) and hepatitis B virus (HBV). Acts as a transcriptional repressor of HBV core promoter.

UniProt: Q8IYM9