GPI antibody (pSer185)

Catalog No. ABIN375349

Product Details anti-GPI Antibody

Target: GPI (Glucose-6-Phosphate Isomerase (GPI))

Binding Specificity: pSer185

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPI antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity: Reacts with human 65 kDa GPI protein with a phosphoserine at position 185

Cross-Reactivity (Details): Do not cross react with non-phospho GPI protein.

Purification: Antiserum

Immunogen: Synthetic peptide derived from human GPI containing a phosphoserine at position 185

Isotype: IgG

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- IHC : 1/200 to 1/1 000 - WB : 1/500 to 1/5 000

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Storage: 4 °C/-20 °C

Storage Comment: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 24 months

Target Details for GPI

Target: GPI (Glucose-6-Phosphate Isomerase (GPI))

Abstract: GPI Products

Synonyms: PGI antibody, Amf antibody, Gpi1 antibody, GPI antibody, DDBDRAFT_0185620 antibody, DDBDRAFT_0231026 antibody, DDB_0185620 antibody, DDB_0231026 antibody, CG8251 antibody, Dmel\\CG8251 antibody, Gpi antibody, pgi antibody, Gpi-1 antibody, Gpi-1r antibody, Gpi-1s antibody, Gpi-1t antibody, Gpi1-r antibody, Gpi1-s antibody, Gpi1-t antibody, Gpi1s antibody, MF antibody, NK antibody, NK/GPI antibody, Org antibody, AMF antibody, GNPI antibody, NLK antibody, PHI antibody, SA-36 antibody, SA36 antibody, gpi antibody, pgi-2 antibody, glucose-6-phosphate isomerase antibody, gpi antibody, glucose-6-phosphate isomerase 1 antibody, gpi Glucose-6-phosphate isomerase antibody, Phosphoglucose isomerase antibody, glucose phosphate isomerase 1 antibody, glucose-6-phosphate isomerase b antibody, GPI antibody, Gpi antibody, gpi antibody, pgi antibody, GPI1 antibody, Pgi antibody, Gpi1 antibody, gpib antibody

Target Type: Viral Protein

Background: Besides it's role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons. Phosphorylation at Ser-185 by CK2 has been shown to decrease enzymatic activity and may contribute to secretion by a non-classical secretory pathway.

UniProt: P06744