GPI antibody (C-Term)

Catalog No. ABIN653743

This Rabbit Polyclonal antibody specifically detects GPI in WB and FACS. It exhibits reactivity toward Human and Mouse. It has been mentioned in 2+ publications

Quick Overview for GPI antibody (C-Term) (ABIN653743)

Target: GPI (Glucose-6-Phosphate Isomerase (GPI))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPI antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: RB24626

Product Details anti-GPI Antibody

Binding Specificity: AA 445-473, C-Term

Predicted Reactivity: Pr

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GPI antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 445-473 amino acids from the C-terminal region of human GPI.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-GPI antibody (ABIN653743)

Jiang, Wang, Wang, Xu, Xu, Tang, Sun, Wang, Zhang: "Enolase1 (ENO1) and glucose-6-phosphate isomerase (GPI) are good markers to predict human sperm freezability." in: Cryobiology, Vol. 71, Issue 1, pp. 141-5, (2015) (PubMed).

Zhao, Li, Liao, Luo, Shi, Feng, Chen: "Evodiamine Induces Apoptosis and Inhibits Migration of HCT-116 Human Colorectal Cancer Cells." in: International journal of molecular sciences, Vol. 16, Issue 11, pp. 27411-21, (2015) (PubMed).

Target Details for GPI

Target: GPI (Glucose-6-Phosphate Isomerase (GPI))

Alternative Name: GPI

Background: GPI belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.

Molecular Weight: 63147

Gene ID: 2821

NCBI Accession: NP_000166, NP_001171651

UniProt: P06744