Prostate Specific Antigen antibody

Catalog No. ABIN179726

The Mouse Monoclonal anti-Prostate Specific Antigen antibody is suitable to detect Prostate Specific Antigen in samples from Human. It has been validated for IHC and FACS.

Quick Overview for Prostate Specific Antigen antibody (ABIN179726)

Target: Prostate Specific Antigen (PSA)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Prostate Specific Antigen antibody is un-conjugated

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: LT-3D2

Product Details anti-Prostate Specific Antigen Antibody

Specificity: Anti-human PSA (glandular kallikrein 3)

Purification: Protein G

Immunogen: genetic immunisation with cDNA encoding human PSA

Isotype: IgG1

Application Details

Application Notes: Flow cytometry: 1.2 µg/10^6 cells
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration.

Restrictions: For Research Use only

Handling

Concentration: 2mg/ml

Buffer: PBS, pH 7.2

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C

Storage Comment: short term: 2 °C - 8 °C, long term: -20 °C

Target Details for Prostate Specific Antigen

Target: Prostate Specific Antigen (PSA)

Alternative Name: PSA

Background: Prostate specific antigen (PSA) belongs to the kallikrein gene family. It is a single-chain glycoprotein with a molecular mass of about 33 kD which is produced by prostate epithelial cells. It is secreted in the seminal plasma and is responsible for liquefaction of the seminal coagulum. PSA is present in small quantities in the serum of healthy males, and is often elevated in the presence of prostate cancer and in other prostate disorders. It is one of the most useful tumour markers because of its tissue specificity. It is thus widely used for screening, diagnosis, and monitoring patients with prostate cancer.

Molecular Weight: 33 kDa

UniProt: P07288

Pathways: Complement System