CD79a antibody (AA 202-216) (FITC)

Catalog No. ABIN181097

Product Details anti-CD79a Antibody (FITC)

Target: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Binding Specificity: AA 202-216

Reactivity: Human, Mouse, Rat, Cow, Pig, Monkey, Chicken, Horse, Rabbit, Guinea Pig, Dog

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD79a antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Specificity: This antibody recognises an epitope within the cytoplasmic domain of CD79a. Species: Human, Monkey, Pig, Horse, Bovine Guinea Pig, Rat, Mouse, Rabbit and Chicken. Others not tested.

Characteristics: Synonyms: IGA, MB1, B-Cell marker, B-cell antigen receptor complex-associated protein alpha-chain,MB-1 membrane glycoprotein, Surface IgM-associated protein, Membrane-boundimmunoglobulin-associated protein

Immunogen: Synthetic peptide corresponding to 202-216 amino acid sequence of Human mb-1. Spleen cells from immunised Balb/c mice were fused with cells of the Sp2/0 myeloma cellline. Genename: CD79a

Clone: HM57

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry: Use 10 µl of Neat-1/5 diluted antibody to label 1x10e6 cells in 100 µl(Membrane permeabilisation is required). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for CD79a

Target: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Alternative Name: CD79a (CD79A Products)

Synonyms: CD79A antibody, Ig-alpha antibody, Iga antibody, Igalpha antibody, Ly-54 antibody, Ly54 antibody, mb-1 antibody, IGA antibody, MB-1 antibody, IG-alpha antibody, CD79a molecule antibody, CD79A antigen (immunoglobulin-associated alpha) antibody, Cd79a molecule-like antibody, CD79A antibody, Cd79a antibody, Cd79al antibody

Background: CD79a, also known as mb-1, is a 45kD protein that is expressed by B lymphocytes duringdifferentiation from early pre-B cell stage through to plasma cells. The CD79a moleculeassociates with CD79b (B29) to form a heterodimer that is non-covalently linked to surfaceimmunoglobulin, forming the B-cell receptor (BCR) complex. The CD79a/CD79bheterodimers are also necessary for intracellular signalling following antigen-binding tosurface immunoglobulin.

UniProt: P11912

Pathways: BCR Signaling