CCR9 antibody (N-Term) (PE)

Catalog No. ABIN1819865

Product Details anti-CCR9 Antibody (PE)

Target: CCR9 (Chemokine (C-C Motif) Receptor 9 (CCR9))

Binding Specificity: N-Term

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CCR9 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Specificity: Detects mouse chemokine receptor 9 (CCR9), also known as CDw199. CCR9 is a seven transmembrane protein which is a member of the beta chemokines receptor family. CCR9 is expressed in thymus and small intestine, and mediates the recruitment and development of thymocytes in response to CCL25, the only known ligand of CCR9. CCR9 is an alternative co-receptor with CD4 for HIV infection, and has been implicated in adult T cell leukaemia. Two alternatively spliced transcript variants have been described. Clone 9B1 blocks CCL25-induced Ca2+ release, attenuating inflammation in a murine model of chronic ileitis when given in early disease stages.

Purification: Protein G purified

Immunogen: 25 amino acids from the amino terminal of murine CCR9, coupled to KLH.

Type of Immunogen: Synthetic peptide

Clone: 9B1

Isotype: IgG2a

Application Details

Application Notes: Approved: Flo (1:1)

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide, 1 % BSA, 5 % sucrose

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing. Protect from light.

Storage: 4 °C,-20 °C

Storage Comment: Short term: store at 4°C. Long term: -20°C. Avoid freeze-thaw cycles. Protect from light.

Target Details for CCR9

Target: CCR9 (Chemokine (C-C Motif) Receptor 9 (CCR9))

Alternative Name: CCR9 (CCR9 Products)

Synonyms: CC-CKR-9 antibody, CDw199 antibody, GPR-9-6 antibody, GPR28 antibody, A130091K22Rik antibody, Cmkbr10 antibody, C-C motif chemokine receptor 9 antibody, chemokine (C-C motif) receptor 9 antibody, CCR9 antibody, Ccr9 antibody

Background: Name/Gene ID: CCR9
Subfamily: Chemokine
Family: GPCR

Synonyms: CCR9, C-C CKR-9, CC-CKR-9, CCR-9, CDw199 antigen, C-C chemokine receptor 9, C-C chemokine receptor type 9, Chemokine c-c motif receptor 9, CDw199, G protein-coupled receptor 28, GPR-9-6, G-protein coupled receptor 28, GPR28

Gene ID: 10803