KIN antibody (Middle Region)

Catalog No. ABIN182401

This Rabbit Polyclonal antibody specifically detects KIN in WB and IHC. It exhibits reactivity toward Human, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit.

Quick Overview for KIN antibody (Middle Region) (ABIN182401)

Target: KIN (KIN, Antigenic Determinant of RecA Protein Homolog (KIN))

Reactivity: Human, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIN antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-KIN Antibody

Binding Specificity: Middle Region

Purpose: KIN Antibody - middle region

Sequence: LKTIGSSASV KRKESSQSST QSKEKKKKKS ALDEIMEIEE EKKRTARTDY

Predicted Reactivity: Cow: 85%, Dog: 85%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Rabbit: 85%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against KIN. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human KIN

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP31690-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for KIN

Target: KIN (KIN, Antigenic Determinant of RecA Protein Homolog (KIN))

Alternative Name: KIN

Background:

Background Information: Kin is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. Short-wave ultraviolet light provokes the relocalization of the protein, suggesting its participation in the cellular response to DNA damage. Originally selected based on protein-binding with RecA antibodies, the mouse protein presents a limited similarity with a functional domain of the bacterial RecA protein, a characteristic shared by the human ortholog.

Gene Name: KIN, antigenic determinant of recA protein homolog (mouse)

Alternative Symbols: BTCD, Rts2, KIN17

Protein Name: DNA/RNA-binding protein KIN17

Molecular Weight: 45kDa

Gene ID: 22944

NCBI Accession: NP_036443

UniProt: O60870