KIN antibody (N-Term)
Quick Overview for KIN antibody (N-Term) (ABIN3042645)
Target
See all KIN AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Purpose
- Anti-DNA/RNA-binding protein KIN17 KIN Antibody
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Sequence
- ESHQRQLLLA SENPQQF
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Specificity
- No cross reactivity with other proteins.
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Cross-Reactivity (Details)
- No cross-reactivity with other proteins
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Predicted Reactivity
- identical to the related mouse,rat sequences.
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Characteristics
- Anti-DNA/RNA-binding protein KIN17 KIN Antibody. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
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Purification
- Immunogen affinity purified.
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Immunogen
- A synthetic peptide corresponding to a sequence at the N-terminus of human KIN, identical to the related mouse and rat sequences.
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Isotype
- IgG
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Application Notes
- Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
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Comment
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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Preservative
- Thimerosal (Merthiolate), Sodium azide
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Precaution of Use
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C,-20 °C
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Storage Comment
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
Expiry Date
- 12 months
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- KIN (KIN, Antigenic Determinant of RecA Protein Homolog (KIN))
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Alternative Name
- KIN
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Background
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Background: DNA/RNA-binding protein KIN17, also known as BTCD or KIN17 is a protein that in humans is encoded by the KIN gene. This gene is mapped to 10p14. The protein encoded by this gene is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. Short-wave ultraviolet light provokes the relocalization of the protein, suggesting its participation in the cellular response to DNA damage. Originally selected based on protein-binding with RecA antibodies, the mouse protein presents a limited similarity with a functional domain of the bacterial RecA protein, a characteristic shared by this human ortholog. Alternative splicing of this gene results in multiple transcript variants.
Gene Full Name: Kin17 DNA and RNA binding protein
Sequence Similarities: Belongs to the KIN17 family.
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Molecular Weight
- 60 kDa
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Gene ID
- 22944
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UniProt
- O60870
Target
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