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Homeobox A2 (HOXA2) (Middle Region) antibody

Details for Product No. ABIN182455
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Antigen
Synonyms hox1k, hoxa2b, X-Hoxa2, hoxa2b-A, HOXA2, HOXA1, Hoxa11, RATHOX111A, HOX1K, AI324701, HOX1.11, Hox-1.11, hoxa2, MGC154497
Epitope
Middle Region
(7), (2), (2), (2), (2), (1)
Reactivity
Rabbit, Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine), Human, Chicken
(12), (7), (2), (2), (2), (2), (1), (1)
Host
Rabbit
(16)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(16), (6)
Pubmed 1 reference available
Quantity 50 µg
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Catalog No. ABIN182455
289.00 $
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Immunogen Synthetic peptide directed towards the middle region of human HOXA2
Sequence GALLEREGYTFQQNALSQQQAPNGHNGDSQSFPVSPLTSN EKNLKHFQHQ
Predicted Reactivity Dog : 100 %, Mouse : 100 %, Rat : 100 %, Rabbit : 90 %, Zebrafish : 70 %
Characteristics This is a rabbit polyclonal antibody against HOXA2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name HOXA2
Background In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development.HOXA2 is a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiateon. HOXA2 may be involved in the placement of hindbrain segments in the proper location along the anterior-posterior axis during development.In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. The encoded protein may be involved in the placement of hindbrain segments in the proper location along the anterior-posterior axis during development.
Molecular Weight 41 kDa
Gene ID 3199
NCBI Accession NM_006735, NP_006726
UniProt O43364
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 376 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Homeobox A2 (HOXA2) (Middle Region) antibody WB Suggested Anti-HOXA2 Antibody Titration: 0.2-1 ug/ml
Positive Control: Human muscle
Background publications Scherer, Cheung, MacDonald et al.: "Human chromosome 7: DNA sequence and biology." in: Science (New York, N.Y.), Vol. 300, Issue 5620, pp. 767-72, 2003 (PubMed).

Validation Images
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