Sirtuin 1 (SIRT1) antibody
| Antigen |
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| Synonyms |
SIR2L1, SIRT1, SIR2, sirtuin 1, SRT1 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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 Alternatives Dog (Canine), Human, Mouse (Murine), Rat (Rattus), Pig (Porcine), Xenopus laevis, Chicken
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Conjugate
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Biotin (5), Alexa Fluor 350 (4), Alexa Fluor 488 (4), Alexa Fluor 555 (4), Alexa Fluor 647 (4), FITC (4), PE,Cy5.5 (4), Cy3 (2), Cy5 (2), Cy5.5 (2), Cy7 (2), Gold (2), HRP (2), PE (2), PE,Cy3 (2), PE,Cy5 (2), PE,Cy7 (2)
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Application
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| Catalog no. |
ABIN182554 |
| Quantity |
50 µg (Variants) |
| Price |
317.90 $ Plus shipping costs $45.00
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Bulk discount
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| Shipping to |
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| Availability |
Will be delivered in 2 to 3 Business Days |
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Alternative name
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SIRT1
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Gene ID
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SIRT1
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UniProt
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Q96EB6
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Immunogen
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The immunogen for anti-SIRT1 antibody: synthetic peptide directed towards the N terminal of human SIRT1
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Sequence
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PETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIEDA VKLLQECKKI
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Cross-Reactivity
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Dog (Canine), Chicken, Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
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Format
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Lyophilized
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Reconstitution
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Add 50 µl of distilled water. Final anti-SIRT1 antibody concentration is 1 mg/ml.
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Description
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SIRT1 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined,
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Characteristics
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Antigen Size: 747 amino acids
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Molecular Weight
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82kDa
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Purification
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Affinity Purified
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Buffer
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PBS
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Storage (Long Term)
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For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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Storage (Short Term)
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Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.
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Research Area
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Chromatin and Nuclear Signaling, Apoptosis/Necrosis, Proteases
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Restrictions
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For Research Use only
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Product
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Solomon, Pasupuleti, Xu et al.: "Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage." in: Molecular and cellular biology, Vol. 26, Issue 1, pp. 28-38, 2005 (PubMed).
Anavekar, Mirza, Skali et al.: "Risk assessment in patients with depressed left ventricular function after myocardial infarction using the myocardial performance index--Survival and Ventricular Enlargement (SAVE) experience." in: Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, Vol. 19, Issue 1, pp. 28-33, 2006 (PubMed).
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Alternatives for antigen "Sirtuin 1 (SIRT1)", type "Antibodies"
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Hosts
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Rabbit (80), Mouse (11), Chicken (3), Goat (3)
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Reactivities
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Human (74), Mouse (Murine) (42), Horse (Equine) (36), Rat (Rattus) (28), Dog (Canine) (25), Pig (Porcine) (23), Chicken (19), Cow (Bovine) (19), Monkey (2), Cat (Feline) (1)
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Applications
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Western Blotting (WB) (53), Immunofluorescence (IF) (48), ELISA (40), Immunohistochemistry (IHC) (15), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (15), Immunoprecipitation (IP) (8), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (6), Flow Cytometry (FACS) (3), Immunocytochemistry (ICC) (3), Immunoelectron Microscopy (IEM) (2)
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Conjugates
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Biotin (5), Alexa Fluor 350 (4), Alexa Fluor 488 (4), Alexa Fluor 555 (4), Alexa Fluor 647 (4), FITC (4), PE,Cy5.5 (4), Cy3 (2), Cy5 (2), Cy5.5 (2), Cy7 (2), Gold (2), HRP (2), PE (2), PE,Cy3 (2), PE,Cy5 (2), PE,Cy7 (2)
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Epitopes
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N-Term (10), C-Term (4), pSer27 (4), pSer47 (4), AA 551-599 (1), AA 577-590 (1), AA 646-660 (1), Center (1), pSer171 (1), pSer257 (1)
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2013 BioMed Central Research Awards
