anti-HSF4 antibody (Heat Shock Transcription Factor 4) (Middle Region)

Details for Product anti-HSF4 Antibody No. ABIN182633, Supplier: Login to see New
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Antigen
Alternatives
Epitope
Middle Region
(18), (16), (6), (5), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(56), (11), (2)
Host
Rabbit
(42), (16), (2)
Clonality
Polyclonal
Conjugate
This HSF4 antibody is un-conjugated
(2), (2), (2), (2), (2), (2)
Application
Western Blotting (WB)
(54), (35), (5), (2), (2), (2), (1), (1)
Pubmed 2 references available
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Quantity 100 μg
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Immunogen Synthetic peptide directed towards the middle region of human HSF4
Sequence VTLRQSHGQQ HRVIGKLIQC LFGPLQAGPS NAGGKRKLSL MLDEGSSCPT
Predicted Reactivity Human : 100 %, Rabbit : 90 %
Characteristics This is a rabbit polyclonal antibody against HSF4. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Alternative Name HSF4 (HSF4 Antibody Abstract)
Background Heat-shock transcription factors (HSFs) activate heat-shock response genes under conditions of heat or other stresses. HSF4 lacks the carboxyl-terminal hydrophobic repeat which is shared among all vertebrate HSFs and has been suggested to be involved in the negative regulation of DNA binding activity. Two alternatively spliced transcripts encoding distinct isoforms and possessing different transcriptional activity have been described.
Molecular Weight 50 kDa
Gene ID 3299
NCBI Accession NM_001538, NP_001529
Research Area Chromatin and Nuclear Signaling, Chromatin Binding Proteins, Transcription Factors
Pathways MAPK Signaling
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 463 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-HSF4 antibody (Heat Shock Transcription Factor 4) (Middle Region) (ABIN182633) WB Suggested Anti-HSF4 Antibody Titration: 5.0ug/ml
ELISA Titer: 1:3...
Product cited in: Lazrek, Goffard, Schanen et al.: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, 2006 (PubMed).

Background publications Kimura, Wakamatsu, Suzuki et al.: "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. ..." in: Genome research, Vol. 16, Issue 1, pp. 55-65, 2006 (PubMed).